Faculty of Medicine. University of Salamanca. Salamanca, (Spain) Patients care, Preparing for specialist in Hematology (research)

Transcripción

1 Curriculum Vitae PERSONAL INFORMATION Jose Maria Moraleda WORK EXPERIENCE June 1977 June 1980 Resident, Medicine. Faculty of Medicine. University of Salamanca. Salamanca, (Spain) Patients care, Preparing for specialist in Hematology (research) June 1980 June 1990 Assistant Professor Faculty of Medicine. University of Salamanca. Salamanca, (Spain) Teaching of of Pathology and Medical Clinic for medical students. June 1981 June 1990 Adjunct-Physician Service of Hematology. University Hospital of Salamanca. Salamanca, (Spain) Hematologic diagnostics; Clinical pathology; Hematopathology; Hematology; Laboratory medicine; Molecular diagnostics; Coagulation disorders/bleeding problems; Hypercoagulable states; Anemias; Hemoglobinopathies; Platelet disorders; Polycythemia; Thrombocytosis; Thrombocytopenia; Sickle cell disease; Hodgkin's disease; Non-Hodgkin's Lymphoma; Multiple myeloma; Monoclonal gammopathy of unknown significance; Myeloprolipherative neoplasms; Myelodysplastic syndromes; Acute leukemias; Clinical trials for focus on translational research; Bone marrow transplant (including stem cell support); Graft-versus-host disease. February 1987 July 1987 Research Fellow Hammersmith Hospital. RPMS. London, (United Kingdom) Clinical and research training in general Hematology and Bone Marrow Transplantation. August 1987 August 1987 Research Fellow University College. Londres, (United Kingdom) Training in autologous bone marrow transplantation and bone marrow cultures. July 1991 February 1993 Adjunct-Physician Service of Hematology. University hospital of Morales Meseguer. Murcia, (Spain) Hematologic diagnostics; Clinical pathology; Hematopathology; Hematology; Laboratory medicine; Molecular diagnostics; Coagulation disorders/bleeding problems; Hypercoagulable states; Anemias; Hemoglobinopathies; Platelet disorders; Polycythemia; Thrombocytosis; Thrombocytopenia; Sickle cell disease; Hodgkin's disease; Non-Hodgkin's Lymphoma; Multiple myeloma; Monoclonal gammopathy of unknown significance; Myeloprolipherative neoplasms; Myelodysplastic syndromes; Acute leukemias; Clinical trials for focus on translational research; Bone marrow transplant (including stem cell support); Graft-versus-host disease European Union, Page 1 / 24

2 October 1993 December 1994 Research Fellow Fred Hutchinson CRC. Seattle. WA, (United States) Training in bone marrow transplantation (incompatible family donors, unrelated donors, allogeneic peripheral stem cells, transplantation in solid tumors, transplantation in children). Research on the impact of immunotherapy in the treatment of residual disease. Training in immunological techniques to monitor treatment with interleukins "in vivo". Training in immunomodulatory and antitumor effects of interleukin-2. February 1993 July 2004 Professor of Medicine Faculty of Medicine. University of Murcia. Murcia, (Spain) Teaching of Hematology for medical students. February 1993 December 2006 Chief of section Service of Hematology. University hospital Morales Meseguer. Murcia, (Spain) Hematologic diagnostics; Hodgkin's disease; Non-Hodgkin's Lymphoma; Multiple myeloma; Monoclonal gammopathy of unknown significance; Myeloprolipherative neoplasms; Myelodysplastic syndromes; Acute leukemias; Clinical trials for focus on translational research; Bone marrow transplant (including stem cell support); Graft-versus-host disease. January 2007 January 2007 Research Fellow Hospital of the Jesus Child. Madrid, (Spain) Training in bone marrow transplantation (transplantation in children). July 2004 Present Professor University Faculty of Medicine. University of Murcia. Murcia, (Spain) Teaching of Hematology for medical students. January 2007 April 2012 Chief of section University Hospital Virgen de La Arrixaca. Murcia, (Spain) Hematologic diagnostics; Hodgkin's disease; Non-Hodgkin's Lymphoma; Multiple myeloma; Monoclonal gammopathy of unknown significance; Myeloprolipherative neoplasms; Myelodysplastic syndromes; Acute leukemias; Clinical trials for focus on translational research; Bone marrow transplant (including stem cell support); Graft-versus-host disease. April 2012 Present Chief, Section of Hematology University Hospital Virgen de La Arrixaca. Murcia, (Spain) Hematologic diagnostics; Hodgkin's disease; Non-Hodgkin's Lymphoma; Multiple myeloma; Monoclonal gammopathy of unknown significance; Myeloprolipherative neoplasms; Myelodysplastic syndromes; Acute leukemias; Clinical trials for focus on translational research; Bone marrow transplant (including stem cell support); Graft-versus-host disease European Union, Page 2 / 24

3 EDUCATION AND TRAINING September 1970 June 1976 Medicine and Surgery. Licenciate University of Navarra. Navarra, (Spain) Excellent July 1986 July 1986 Medicine and Surgery. Doctorate University of Salamanca. Salamanca, (Spain) Cum Laude June 2004 June 2004 Medicine Service of Hematology. Professor University of Murcia. Murcia, (Spain) ADDITIONAL INFORMATION Expertise Clinical trials for focus on translational research. Hematopoietic stem cell transplant: Autologous and allogeneic. Bone marrow, Peripheral blood, Umbilical cord. Myeloablative and Non-myeloablative. Related and unrelated donor. Immunotherapy. Graft-versus-host disease. Extracorporeal photopheresis. Stem Cell Therapy for repair of damaged tissues and organs (epithelialisation of massive posttraumatic wounds, vascular ischemia, bone repair, transplant rejection and GVHD, ophthalmology, odontology, neurodegenerative Diseases. Publications Autologous stem cell transplantation after conditioning with Yttrium-90 ibritumomab tiuxetan plus beam in refractory non-hodgkin diffuse large B-cell lymphoma: results of a prospective, multicenter, phase II clinical trial. Briones J, Novelli S, García-Marco JA, Tomás JF, Bernal T, Grande C, Canales MA, Torres A,Moraleda JM, Panizo C, Jarque I, Palmero F, Hernsández M, González-Barca E, López D, Caballero D. Haematologica Oct 25. [Epub ahead of print] PMID: Acute and chronic MRI changes in the spine and spinal cord after surgical stem cell grafting in patients with definite amyotrophic lateral sclerosis: post-infusion injuries are unrelated with clinical impairment. García Santos JM, Blanquer M, Torres del Río S, Iniesta F, Espuch JG, Pérez-Espejo MÁ, Martínez S,Moraleda JM. Magn Reson Imaging Oct;31(8): doi: /j.mri Epub 2013 Jun 28. PMID: Cell therapy in bisphosphonate-related osteonecrosis of the jaw. Gonzálvez-García M, Rodríguez-Lozano FJ, Villanueva V, Segarra-Fenoll D, Rodríguez-González MA, Oñate-Sánchez R, Blanquer M, Moraleda JM. J Craniofac Surg May;24(3):e doi: /SCS.0b013e PMID: Clonazepam for seizure prophylaxis in adult patients treated with high dose busulfan. Diaz-Carrasco MS, Olmos R, Blanquer M, Velasco J, Sánchez-Salinas A, Moraleda JM. Int J Clin Pharm Jun;35(3): doi: /s x. Epub 2013 Apr European Union, Page 3 / 24

4 PMID: Effects of two low-shrinkage composites on dental stem cells (viability, cell damaged or apoptosis and mesenchymal markers expression). Rodríguez-Lozano FJ, Serrano-Belmonte I, Pérez Calvo JC, Coronado-Parra MT, Bernabeu- Esclapez A, Moraleda JM. J Mater Sci Mater Med Apr;24(4): doi: /s x. Epub 2013 Jan 26. PMID: Bone marrow transplantation in hindlimb muscles of motoneuron degenerative mice reduces neuronal death and improves motor function. Pastor D, Viso-León MC, Botella-López A, Jaramillo-Merchan J, Moraleda JM, Jones J, Martínez S. Stem Cells Dev Jun 1;22(11): doi: /scd Epub 2013 Feb 13. PMID: Tissue engineering with dental pulp stem cells: isolation, characterization, and osteogenic differentiation. Rodríguez-Lozano FJ, Insausti CL, Meseguer L, Ramírez MC, Martínez S, Moraleda JM. J Craniofac Surg Nov;23(6):e doi: /SCS.0b013e31825e4e16. PMID: Human adult periodontal ligament-derived cells integrate and differentiate after implantation into the adult Mammalian brain. Bueno C, Ramirez C, Rodríguez-Lozano FJ, Tabarés-Seisdedos R, Rodenas M, Moraleda JM, Jones JR, Martinez S. Cell Transplant. 2013;22(11): doi: / X Epub 2012 Oct 3. PMID: Autocrine TGF-β induces epithelial to mesenchymal transition in human amniotic epithelial cells. Alcaraz A, Mrowiec A, Insausti CL, García-Vizcaíno EM, Ruiz-Canada C, López-Martínez MC,Moraleda JM, Nicolás FJ. Cell Transplant. 2013;22(8): doi: / X Epub 2012 Oct 2. PMID: Isolation and characterization of mesenchymal stem cells from the fat layer on the density gradient separated bone marrow. Insausti CL, Blanquer MB, Olmo LM, López-Martínez MC, Ruiz XF, Lozano FJ, Perianes VC, Funes C, Nicolás FJ, Majado MJ, Jiménez JM. Stem Cells Dev Jan 20;21(2): doi: /scd Epub 2011 Jun 10. PMID: Mesenchymal dental stem cells in regenerative dentistry. Rodríguez-Lozano FJ, Insausti CL, Iniesta F, Blanquer M, Ramírez MD, Meseguer L, Meseguer- Henarejos AB, Marín N, Martínez S, Moraleda JM. Med Oral Patol Oral Cir Bucal Nov 1;17(6):e Review. PMID: Mesenchymal stem cells and bisphosphonate-related osteonecrosis of the jaw: the future? Gonzálvez-García M, Rodríguez-Lozano FJ, Villanueva V, Segarra-Fenoll D, Rodríguez-González MA, Oñate-Sánchez R, Blanquer M, Meseguer-Olmo L, Moraleda JM. Oral Dis Nov;18(8): doi: /j x. Epub 2012 Aug 23. No abstract available. PMID: Neurotrophic bone marrow cellular nests prevent spinal motoneuron degeneration in amyotrophic lateral sclerosis patients: a pilot safety study. Blanquer M, Moraleda JM, Iniesta F, Gómez-Espuch J, Meca-Lallana J, Villaverde R, Pérez-Espejo MÁ, Ruíz-López FJ, García Santos JM, Bleda P, Izura V, Sáez M, De Mingo P, Vivancos L, Carles R, Jiménez J, Hernández J, Guardiola J, Del Rio ST, Antúnez C, De la Rosa P, Majado MJ, Sánchez- Salinas A, López J, Martínez-Lage JF, Martínez S European Union, Page 4 / 24

5 Stem Cells Jun;30(6): doi: /stem PMID: Pure red cell aplasia in a simultaneous pancreas-kidney transplantation patient: inside the erythroblast. Labbadia F, Salido-Fierréz E, Majado-Martinez J, Cabañas-Perianes V, Moraleda JJ. Hematol Rep Jul 11;4(3):e17. doi: /hr.2012.e17. Epub 2012 Sep 10. PMID: An automatic wash method for dimethyl sulfoxide removal in autologous hematopoietic stem cell transplantation decreases the adverse effects related to infusion. Sánchez-Salinas A, Cabañas-Perianes V, Blanquer M, Majado MJ, Insausti CL, Monserrat J, Sánchez-Ibáñez MV, Menchón P, García-Hernández A, Gómez-Espuch J, Morales A, Moraleda JM. Transfusion Nov;52(11): doi: /j x. Epub 2012 Mar 8. PMID: Fabrication of conductive electrospun silk fibroin scaffolds by coating with polypyrrole for biomedical applications. Aznar-Cervantes S, Roca MI, Martinez JG, Meseguer-Olmo L, Cenis JL, Moraleda JM, Otero TF. Bioelectrochemistry Jun;85: doi: /j.bioelechem Epub 2011 Dec 8. PMID: Stage IV and age over 45 years are the only prognostic factors of the International Prognostic Score for the outcome of advanced Hodgkin lymphoma in the Spanish Hodgkin Lymphoma Study Group series. Guisado-Vasco P, Arranz-Saez R, Canales M, Cánovas A, Garcia-Laraña J, García-Sanz R, Lopez A, López JL, Llanos M, Moraleda JM, Rodriguez J, Rayón C, Sabin P, Salar A, Marín-Niebla A, Morente M, Sánchez-Godoy P, Tomás JF, Muriel A, Abraira V, Piris MA, Garcia JF, Montalban C; Spanish Hodgkin Lymphoma Study Group. Leuk Lymphoma May;53(5): doi: / Epub 2012 Jan 31. PMID: Use of dental stem cells in regenerative dentistry: a possible alternative. Rodríguez-Lozano FJ, Moraleda JM. Transl Res Dec;158(6): doi: /j.trsl Epub 2011 Aug 24. No abstract available. PMID: Comparative effects between bone marrow and mesenchymal stem cell transplantation in GDNF expression and motor function recovery in a motorneuron degenerative mouse model. Pastor D, Viso-León MC, Jones J, Jaramillo-Merchán J, Toledo-Aral JJ, Moraleda JM, Martínez S. Stem Cell Rev Jun;8(2): doi: /s x. PMID: Skin nodules in multiple myeloma. Cabañas-Perianes V, Jiménez JM. Blood Feb 17;117(7):2088. No abstract available. PMID: [Radiosurgery as adjuvant treatment of a recurrent adult medulloblastoma. Ultra-early response]. Pérez-Espejo MA, Tobarra-González BM, Piqueras-Pérez CJ, Sola-Pérez J, Torroba A, Sánchez- Salinas A, Moraleda-Jiménez JM, de la Fuente-Muñoz I, García-Fernández R, López-Soler F, Martínez-Lage JF, Fernández-Pérez J. Neurocirugia (Astur) Dec;22(6): Spanish. PMID: Long-term prognostic significance of response in multiple myeloma after stem cell transplantation. Martinez-Lopez J, Blade J, Mateos MV, Grande C, Alegre A, García-Laraña J, Sureda A, de la Rubia J, Conde E, Martinez R, de Arriba F, Viguria MC, Besalduch J, Cabrera R, Gonzalez-San Miguel JD, Guzman-Zamudio JL, Gomez del Castillo MC, Moraleda JM, García-Ruiz JC, San Miguel J, Lahuerta European Union, Page 5 / 24

6 JJ; Grupo Español de MM; Programa para el Estudio de la Terapé utica en Hemopatía Maligna. Blood Jul 21;118(3): doi: /blood Epub 2011 Apr 11. PMID: Mesenchymal stem cells derived from dental tissues. Rodríguez-Lozano FJ, Bueno C, Insausti CL, Meseguer L, Ramírez MC, Blanquer M, Marín N, Martínez S, Moraleda JM. Int Endod J Sep;44(9): doi: /j x. Epub 2011 Apr 8. Review. PMID: Mesenchymal dental pulp stem cells: a new tool in sinus lift. Rodríguez Lozano FJ, Moraleda JM. J Craniofac Surg Mar;22(2): doi: /SCS.0b013e318208ba61. No abstract available. PMID: Cryopreservation impact on blood progenitor cells: influence of diagnoses, mobilization treatments, and cell concentration. Majado MJ, Salgado-Cecilia G, Blanquer M, Funes C, González-García C, Insausti CL, Parrado A, Morales A, Minguela A, Moraleda JM. Transfusion Apr;51(4): doi: /j x. Epub 2010 Sep 28. PMID: [Bone marrow stem cell transplantation in amyotrophic lateral sclerosis: technical aspects and preliminary results from a clinical trial]. Blanquer M, Pérez Espejo MA, Iniesta F, Gómez Espuch J, Meca J, Villaverde R, Izura V, de Mingo P, Martínez-Lage J, Martínez S, Moraleda JM. Methods Find Exp Clin Pharmacol Dec;32 Suppl A:31-7. Spanish. PMID: Splenic rupture in a plasma cell leukemia, mobilized with G-CSF for autologous stem cell transplant. Funes C, Garcia-Candel F, Majado MJ, González-García C, Bas A, Salido E, Moraleda JM, Morales A. J Clin Apher. 2010;25(4): doi: /jca PMID: Amniotic membrane induces epithelialization in massive posttraumatic wounds. Insausti CL, Alcaraz A, García-Vizcaíno EM, Mrowiec A, López-Martínez MC, Blanquer M, Piñero A, Majado MJ, Moraleda JM, Castellanos G, Nicolás FJ. Wound Repair Regen Jul-Aug;18(4): doi: /j X x. PMID: A surgical technique of spinal cord cell transplantation in amyotrophic lateral sclerosis. Blanquer M, Pérez-Espejo MA, Martínez-Lage JF, Iniesta F, Martinez S, Moraleda JM. J Neurosci Methods Aug 30;191(2): doi: /j.jneumeth Epub 2010 Jun 23. PMID: Immunophenotype of acute myeloid leukemia with NPM mutations: prognostic impact of the leukemic compartment size. Nomdedeu J, Bussaglia E, Villamor N, Martinez C, Esteve J, Tormo M, Estivill C, Queipo MP, Guardia R, Carricondo M, Hoyos M, Llorente A, Juncà J, Gallart M, Domingo A, Bargay J, Mascaró M,Moraleda JM, Florensa L, Ribera JM, Gallardo D, Brunet S, Aventin A, Sierra J; Spanish CETLAM. Leuk Res Feb;35(2): doi: /j.leukres Epub 2010 Jun 9. PMID: A molecular risk score based on 4 functional pathways for advanced classical Hodgkin lymphoma. Sánchez-Espiridión B, Montalbán C, López A, Menárguez J, Sabín P, Ruiz-Marcellán C, Lopez A, Ramos R, Rodríguez J, Cánovas A, Camarero C, Canales M, Alves J, Arranz R, Acevedo A, Salar A, Serrano S, Bas A, Moraleda JM, Sánchez-Godoy P, Burgos F, Rayón C, Fresno MF, Laraña JG, European Union, Page 6 / 24

7 García-Cosío M, Santonja C, López JL, Llanos M, Mollejo M, González-Carrero J, Marín A, Forteza J, García-Sanz R, Tomás JF, Morente MM, Piris MA, García JF; Spanish Hodgkin Lymphoma Study Group. Blood Aug 26;116(8):e12-7. doi: /blood Epub 2010 May 17. PMID: The amniotic membrane as a source of stem cells. Insausti CL, Blanquer M, Bleda P, Iniesta P, Majado MJ, Castellanos G, Moraleda JM. Histol Histopathol Jan;25(1):91-8. Review. PMID: Large-volume-apheresis facilitates autologous transplantation of hematopoietic progenitors in poor mobilizer patients. Majado MJ, Minguela A, González-García C, Salido E, Blanquer M, Funes C, Insausti CL, García- Hernández AM, Moraleda JM, Morales A. J Clin Apher. 2009;24(1):12-7. doi: /jca PMID: Sustained remissions of high-risk acute myeloid leukemia and myelodysplastic syndrome after reduced-intensity conditioning allogeneic hematopoietic transplantation: chronic graft-versus-host disease is the strongest factor improving survival. Valcárcel D, Martino R, Caballero D, Martin J, Ferra C, Nieto JB, Sampol A, Bernal MT, Piñana JL, Vazquez L, Ribera JM, Besalduch J, Moraleda JM, Carrera D, Brunet MS, Perez-Simón JA, Sierra J. J Clin Oncol Feb 1;26(4): Epub 2007 Dec 17. PMID: Prolonged survival of patients with angioimmunoblastic T-cell lymphoma after high-dose chemotherapy and autologous stem cell transplantation: the GELTAMO experience. Rodríguez J, Conde E, Gutiérrez A, Arranz R, Gandarillas M, Leon A, Ojanguren J, Sureda A, Carrera D, Bendandi M, Moraleda J, Ribera JM, Albo C, Morales A, García JC, Fernández P, Cañigral G, Bergua J, Caballero MD; Grupo Español de Linfomas/Trasplante Autólogo de Médula Osea. Eur J Haematol Apr;78(4): PMID: Adult stem cell therapy: dream or reality? Moraleda JM, Blanquer M, Bleda P, Iniesta P, Ruiz F, Bonilla S, Cabanes C, Tabares L, Martinez S. Transpl Immunol Dec;17(1):74-7. Epub 2006 Oct 16. Review. PMID: Nonmyeloablative stem cell transplantation is an effective therapy for refractory or relapsed hodgkin lymphoma: results of a spanish prospective cooperative protocol. Alvarez I, Sureda A, Caballero MD, Urbano-Ispizua A, Ribera JM, Canales M, García-Conde J, Sanz G, Arranz R, Bernal MT, de la Serna J, Díez JL, Moraleda JM, Rubió-Félix D, Xicoy B, Martínez C, Mateos MV, Sierra J. Biol Blood Marrow Transplant Feb;12(2): PMID: Reduced-intensity conditioning allogeneic transplantation is associated with a high incidence of extramedullary relapses in multiple myeloma patients. Pérez-Simón JA, Sureda A, Fernández-Aviles F, Sampol A, Cabrera JR, Caballero D, Martino R, Petit J, Tomás JF, Moraleda JM, Alegre A, Cañizo C, Brunet S, Rosiñol L, Lahuerta J, Díez-Martín JL, León A, García A, Vazquez L, Sierra J, San Miguel JF; Grupo Español de Mieloma. Leukemia Mar;20(3): No abstract available. PMID: [Prevalence and prognostic significance of myeloid markers in adults with high-risk acute lymphoblastic leukemia]. Plensa E, Ribera JM, Oriol A, Bethencourt C, Parody R, Hernández Ribas JM, Moreno MJ, del Potro E, Tormo M, Rivas C, Besalduch J, Sanz MA, Arias J, Fernández Calvo J, Moraleda JM, Bueno J, Feliu E, Ortega JJ; Grupo PETHEMA European Union, Page 7 / 24

8 Med Clin (Barc) Sep 3;125(7): Spanish. PMID: Prognostic factors affecting long-term outcome after stem cell transplantation in Hodgkin's lymphoma autografted after a first relapse. Sureda A, Constans M, Iriondo A, Arranz R, Caballero MD, Vidal MJ, Petit J, López A, Lahuerta JJ, Carreras E, García-Conde J, García-Laraña J, Cabrera R, Jarque I, Carrera D, García-Ruiz JC, Pascual MJ, Rifón J, Moraleda JM, Pérez-Equiza K, Albó C, Díaz-Mediavilla J, Torres A, Torres P, Besalduch J, Marín J, Mateos MV, Fernández-Rañada JM, Sierra J, Conde E; Grupo Español de Linfomas/Trasplante Autólogo de Médula Osea Cooperative Group. Ann Oncol Apr;16(4): Epub 2005 Feb 28. PMID: [Economic cost of peripheral blood progenitor cell transplantation in Spain]. Sánchez-Blanco JJ, Lozano ML, de Arriba F, Vallejo C, Vicente V, Moraleda JM. Med Clin (Barc) Oct 2;123(11): Spanish. PMID: Human platelet antigen systems in allogeneic peripheral blood progenitor cell transplantation: effect of human platelet antigen mismatch on platelet engraftment and graft-versus-host disease. García-Malo MD, Corral J, González M, Solano C, González-Conejero R, Caballero MD, Pérez R,Moraleda JM, Vicente V. Transfusion May;44(5): PMID: Elderly age and prior autologous transplantation have a deleterious effect on survival following allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning: results from the Spanish multicenter prospective trial. Gómez-Núñez M, Martino R, Caballero MD, Pérez-Simón JA, Canals C, Mateos MV, Sarrá J, León A, Solano C, Moraleda JM, Urbano-Ispizua A, Besalduch J, Miguel JS, Sierra J. Bone Marrow Transplant Mar;33(5): PMID: Genetic polymorphisms of platelet adhesive molecules: association with breast cancer risk and clinical presentation. Ayala F, Corral J, González-Conejero R, Sánchez I, Moraleda JM, Vicente V. Breast Cancer Res Treat Jul;80(2): PMID: A systematic review of the antifungal effectiveness and tolerability of amphotericin B formulations. Barrett JP, Vardulaki KA, Conlon C, Cooke J, Daza-Ramirez P, Evans EG, Hawkey PM, Herbrecht R, Marks DI, Moraleda JM, Park GR, Senn SJ, Viscoli C; Amphotericin B Systematic Review Study Group. Clin Ther May;25(5): Review. PMID: Positive selection for CD34+ reduces the incidence and severity of veno-occlusive disease of the liver after HLA-identical sibling allogeneic peripheral blood stem cell transplantation. Moscardó F, Urbano-Ispizua A, Sanz GF, Brunet S, Caballero D, Vallejo C, Solano C, Pimentel P, Pérez de Oteyza J, Ferrá C, Díez-Martín JL, Zuazu J, Espigado I, Campilho F, Arbona C, Moraleda JM, Mateos MV, Sierra J, Talarn C, Sanz MA. Exp Hematol Jun;31(6): PMID: Massive intestinal infiltration in a patient with bone T-cell rich diffuse large B cell lymphoma. Blanquer M, Cava C, Ruiz FM, Cascales A, Cascales A, de Arriba F, Moraleda JM, Vicente V. Haematologica May;88(5):EIM05. No abstract available. PMID: Autologous stem cell transplantation for primary refractory Hodgkin's disease: results and clinical variables affecting outcome European Union, Page 8 / 24

9 Constans M, Sureda A, Terol MJ, Arranz R, Caballero MD, Iriondo A, Jarque I, Carreras E, Moraleda JM, Carrera D, León A, López A, Albó C, Díaz-Mediavilla J, Fernández-Abellán P, García-Ruiz JC, Hernández-Navarro F, Mataix R, Petit J, Pascual MJ, Rifón J, García-Conde J, Fernández-Rañada JM, Mateos MV, Sierra J, Conde E; GEL/TAMO Cooperative Group. Ann Oncol May;14(5): PMID: Low incidence of secondary myelodysplasia and acute myeloid leukemia after high-dose chemotherapy as adjuvant therapy for breast cancer patients: a study by the Solid Tumors Working Party of the European Group for Blood and Marrow Transplantation. Kröger N, Zander AR, Martinelli G, Ferrante P, Moraleda JM, Da Prada GA, Demirer T, Socie G, Rosti G; European Group for Blood and Marrow Transplantation. Ann Oncol Apr;14(4): PMID: High-dose therapy in diffuse large cell lymphoma: results and prognostic factors in 452 patients from the GEL-TAMO Spanish Cooperative Group. Caballero MD, Pérez-Simón JA, Iriondo A, Lahuerta JJ, Sierra J, Marín J, Gandarillas M, Arranz R, Zuazu J, Rubio V, Fernández de Sevilla A, Carreras E, García-Conde J, García-Laraña J, Grande C, Sureda A, Vidal MJ, Rifón J, Pérez-Equiza C, Varela R, Moraleda JM, García Ruíz JC, Albó C, Cabrera R, San Miguel JF, Conde E. Ann Oncol Jan;14(1): PMID: Report of recombinations between HLA loci within two families: utility of high resolution typing. Muro M, Moya-Quiles MR, Marin L, Torío A, Vallejo C, Moraleda JM, Alvarez-López MR. Clin Transplant Oct;16(5): PMID: Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous leukemia and myelodysplastic syndromes. Martino R, Caballero MD, Pérez-Simón JA, Canals C, Solano C, Urbano-Ispízua A, Bargay J, Léon A, Sarrá J, Sanz GF, Moraleda JM, Brunet S, San Miguel J, Sierra J; AML and allopbsct Subcommittees of the Spanish Group for Hematopoietic Transplantation. Blood Sep 15;100(6): Erratum in: Blood Dec 15;112(13):5259. Simón, José Antonio Pérez [corrected to Pérez-Simón, José Antonio]. PMID: Are myeloma patients with renal failure candidates for autologous stem cell transplantation? San Miguel JF, Lahuerta JJ, García-Sanz R, Alegre A, Bladé J, Martinez R, García-Laraña J, De La Rubia J, Sureda A, Vidal MJ, Escudero A, Pérez-Esquiza E, Conde E, García-Ruiz JC, Cabrera R, Caballero D, Moraleda JM, Leon A, Besalduch J, Hernandez MT, Rifon J, Hernandez F, Solano C, Palomera L, Parody R, Gonzalez JD, Mataix R, Maldonado J, Constela J, Carrera D, Bello JL, De Pablos JM, Pérez-Simón JA, Torres JP, Olanguren J, Prieto E, Acebede G, Peñarrubia MJ, Torres P, Díez-Martín JL, Rivas A, Sánchez JM, Díaz-Mediavilla J. Hematol J. 2000;1(1): PMID: Severe infections after allogeneic peripheral blood stem cell transplantation: a matched-pair comparison of unmanipulated and CD34+ cell-selected transplantation. Martino R, Rovira M, Carreras E, Solano C, Jorge S, De La Rubia J, Caballero MD, de Oteyza JP, Zuazu J, Moraleda JM, Ojeda E, Ferrá C, Serrano D, De La Cámara R, Urbano-Ispízua A, Brunet S; AlloPBSCT and Infectious/Non-infectious Complications Subcommittes of the Grupo Español de Trasplante Hematopoyético (GETH). Haematologica Oct;86(10): PMID: Allogeneic transplantation of CD34+-selected cells from peripheral blood in patients with myeloid malignancies in early phase: a case control comparison with unmodified peripheral blood transplantation. Urbano-Ispizua A, Brunet S, Solano C, Moraleda JM, Rovira M, Zuazu J, de La Rubia J, Bargay J, European Union, Page 9 / 24

10 Caballero D, Díez-Martín JL, Ojeda E, Pérez de Oteiza JP, Ferrá C, Espigado I, Alegre A, de La Serna J, Torres P, Riu C, Odriozola J, Rozman C, Sierra J, García-Conde J, Montserrat E; Spanish Group of Allo-PBT. Bone Marrow Transplant Aug;28(4): PMID: Favourable effect of the combination of acute and chronic graft-versus-host disease on the outcome of allogeneic peripheral blood stem cell transplantation for advanced haematological malignancies. Brunet S, Urbano-Ispizua A, Ojeda E, Ruiz D, Moraleda JM, Díaz MA, Caballero D, Bargay J, de la Rubia J, Solano C, Zuazu J, Diez JL, de la Serna J, Espigado I, Alegre A, Torres JP, Jurado M, Fernández M, Vivancos P, Carreras E, Hernández F, Maldonado J, Sierra J, Rozman C; Spanish Group of Allogenic-PBT, Spain. Br J Haematol Sep;114(3): PMID: Administration of post-autologous PBSCT rhg-csf is associated with long-term low concentrations of bone marrow hematopoietic progenitor cells. Osma MM, Ortuño F, Lozano ML, Gomez-Espuch J, Ayala F, Sanchez-Serrano I, Perez-Ceballos E,Moraleda JM, Vicente V. Bone Marrow Transplant Jun;27(12): PMID: Autologous stem-cell transplantation for Hodgkin's disease: results and prognostic factors in 494 patients from the Grupo Español de Linfomas/Transplante Autólogo de Médula Osea Spanish Cooperative Group. Sureda A, Arranz R, Iriondo A, Carreras E, Lahuerta JJ, García-Conde J, Jarque I, Caballero MD, Ferrà C, López A, García-Laraña J, Cabrera R, Carrera D, Ruiz-Romero MD, León A, Rifón J, Díaz- Mediavilla J, Mataix R, Morey M, Moraleda JM, Altés A, López-Guillermo A, de la Serna J, Fernández-Rañada JM, Sierra J, Conde E; Grupo Español de Linformas/Transplante Autólogo de Médula Osea Spanish Cooperative Group. J Clin Oncol Mar 1;19(5): PMID: Fatal upper and lower gastrointestinal cytomegalovirus disease following autologous peripheral blood stem cell transplantation. Perez-Ceballos E, Vallejo C, Cano H, Ayala F, Martínez F, Moraleda J, Vicente V. Eur J Haematol Feb;66(2): PMID: Resolution of cyclosporine-induced gingival hyperplasia resistant to azithromycin by switching to tacrolimus. Vallejo C, Iniesta P, Moraleda JM. Haematologica Jan;86(1):110. No abstract available. PMID: Re-mobilization of peripheral blood progenitor cells within a short time interval fails to achieve effective progenitor cell yields. Vallejo C, Lozano ML, Ortuño F, Moraleda JM, Vicente V. Bone Marrow Transplant Aug;26(3): PMID: Remission status defined by immunofixation vs. electrophoresis after autologous transplantation has a major impact on the outcome of multiple myeloma patients. Lahuerta JJ, Martinez-Lopez J, Serna JD, Bladé J, Grande C, Alegre A, Vazquez L, García-Laraña J, Sureda A, Rubia JD, Conde E, Martinez R, Perez-Equiza K, Moraleda JM, León A, Besalduch J, Cabrera R, Miguel JD, Morales A, García-Ruíz JC, Diaz-Mediavilla J, San-Miguel J. Br J Haematol May;109(2): PMID: Conditioning regimens in autologous stem cell transplantation for multiple myeloma: a comparative study of efficacy and toxicity from the Spanish Registry for Transplantation in Multiple Myeloma European Union, Page 10 / 24

11 Lahuerta JJ, Martinez-Lopez J, Grande C, Bladé J, de la Serna J, Alegre A, García-Laraña J, Caballero D, Sureda A, de la Rubia J, Alvarez AM, Marín J, Escudero A, Conde E, Perez-Equiza K, García Ruiz JC, Moraleda JM, León A, Bargay J, Cabrera R, Hernandez-García MT, Diaz-Mediavilla J, Miguel JS. Br J Haematol Apr;109(1): PMID: Mobilization of hematopoietic progenitor cells with paclitaxel (taxol) as a single chemotheraupetic agent, associated with rhg-csf. Gómez-Espuch J, Moraleda JM, Ortuño F, Lozano ML, Ayala F, Vallejo C, de Arriba F, Vicente V. Bone Marrow Transplant Feb;25(3): PMID: Glycoprotein IIb/IIIa expression on hematopoietic stem cells: constitutive expression or platelet adhesion? Gómez-Espuch J, Corral J, González-Conejero R, Ortuño F, Moraleda JM, Vicente V. Blood Nov 1;94(9): No abstract available. PMID: Antithrombotic therapy after coronary-artery stenting. Ferrer F, Moraleda JM, Vicente V. N Engl J Med Apr 29;340(17):1365; author reply No abstract available. PMID: Autoaggression syndrome resembling acute graft-versus-host disease grade IV after autologous peripheral blood stem cell transplantation for breast cancer. de Arriba F, Corral J, Ayala F, Heras I, Moraleda JM, Osma MM, González-Conejero R, Ortuño F, Vicente V. Bone Marrow Transplant Mar;23(6): PMID: Preleukapheresis peripheral blood CD34+ cells predict progenitor cell collection yield and the necessary number of procedures to undergo. Osma MM, Ortuño F, de Arriba F, Heras I, Moraleda JM, Garcia VV. Haematologica Mar;84(3): No abstract available. PMID: Chronic graft-versus-host disease after allogeneic peripheral blood progenitor cell or bone marrow transplantation from matched related donors. A case-control study. Spanish Group of Allo-PBT. Solano C, Martinez C, Brunet S, Tomás JF, Urbano-Ispizua A, Zuazu J, Ojeda E, Bargay J, Moraleda JM, Bailen A, Sierra J, García-Conde J, Rozman C. Bone Marrow Transplant Dec;22(12): PMID: Polymorphisms of platelet membrane glycoprotein Ib associated with arterial thrombotic disease. Gonzalez-Conejero R, Lozano ML, Rivera J, Corral J, Iniesta JA, Moraleda JM, Vicente V. Blood Oct 15;92(8): PMID: Bone marrow steady-state CD34+/CD71- cell content is a predictive value of rg-csf-mobilized CD34+ cells. Osma MM, Ortuño F, de Arriba F, Lozano ML, Heras I, Moraleda JM, Vicente V. Bone Marrow Transplant May;21(10): PMID: [Other congenital hypercoagulable states]. Vicente V, Rivera J, Corral J, Moraleda JM. Sangre (Barc) Dec;42(6): Review. Spanish. No abstract available. PMID: European Union, Page 11 / 24

12 BEAM chemotherapy followed by autologous stem cell support in lymphoma patients: analysis of efficacy, toxicity and prognostic factors. Caballero MD, Rubio V, Rifon J, Heras I, García-Sanz R, Vázquez L, Vidriales B, del Cañizo MC, Corral M, Gonzalez M, León A, Jean-Paul E, Rocha E, Moraleda JM, San Miguel JF. Bone Marrow Transplant Sep;20(6): PMID: Autologous stem cell transplantation for poor prognosis Hodgkin's disease in first complete remission: a retrospective study from the Spanish GEL-TAMO cooperative group. Sureda A, Mataix R, Hernández-Navarro F, Jarque I, Lahuerta JJ, Tomás JF, Brunet S, Caballero D, Conde E, León A, Fernández MN, López A, Maldonado J, Bengoechea E, Callís M, Carrera D, García-Conde J, García-Laraña J, Moraleda JM, Morey M, Rifón J, Sierra J, Torres A, Domingo-Albós A. Bone Marrow Transplant Aug;20(4): PMID: Differences in phycoerythrin- or fluorescein-isothiocyanate conjugated 8G12 on CD34+ cell evaluation. Ortuño F, Ferrer F, Lozano ML, Heras I, Moraleda JM, Vicente V. Haematologica May-Jun;82(3): PMID: [Allogenic transplant of non-manipulated hematopoietic progenitor peripheral blood cells. Spanish experience of 79 cases. Allo-Peripheral Blood Transplantation Group]. Brunet S, Urbano-Ispizua A, Solano C, Ojeda E, Caballero D, Torrabadella M, de la Rubia J, Pérez- Oteiza J, Moraleda J, Espigado I, de la Serna J, Petit J, Bargay J, Mataix R, Vivancos P, Figuera A, Sierra J, Domingo-Albós A, Hernández F, García Conde J, Rozman C. Sangre (Barc) Apr;42 Suppl 1:42-3. Spanish. No abstract available. PMID: [Maintenance treatment with interferon-alfa in multiple myeloma after autotransplantation of peripheral blood progenitor cells. Spanish Register of Transplantation in Myeloma]. García Laraña J, Díaz Mediavilla J, Martínez R, Lahuerta JJ, Alegre A, Odriozola J, Sureda A, San Miguel J, De la Rubia J, Escudero A, Conde E, Bladé J, Cabrera R, Gastearena J, Besalduch J, Vidal MJ, Hernández F, Rifon J, Leon A, Mataix R, Parody R, Moraleda JM, Solano C, de Pablos JM, Sánchez JJ, et al. Sangre (Barc) Apr;42 Suppl 1: Spanish. No abstract available. PMID: Loss of high-affinity thrombin receptors during platelet concentrate storage impairs the reactivity of platelets to thrombin. Lozano ML, Rivera J, Gónzález-Conejero R, Moraleda JM, Vicente V. Transfusion Apr;37(4): PMID: Disseminated aspergillosis after mobilization with intensive chemotherapy prior to autologous stemcell transplant in chronic myeloid leukemia. Ferrer F, Moraleda JM, Toldos MC, Heras I, Vicente V. Am J Hematol Feb;54(2): No abstract available. PMID: Prospective randomized study comparing the efficacy of bioequivalent doses of glycosylated and nonglycosylated rg-csf for mobilizing peripheral blood progenitor cells. de Arriba F, Lozano ML, Ortuño F, Heras I, Moraleda JM, Vicente V. Br J Haematol Feb;96(2): PMID: Allogeneic peripheral blood progenitor cell transplantation: analysis of short-term engraftment and acute GVHD incidence in 33 cases. allo-pbpct Spanish Group. Urbano-Ispizua A, Solano C, Brunet S, Hernández F, Sanz G, Alegre A, Petit J, Besalduch J, European Union, Page 12 / 24

13 Vivancos P, Díaz MA, Moraleda JM, Carreras E, Ojeda E, de la Rubia J, Benet I, Domingo-Albós A, García-Conde J, Rozman C. Bone Marrow Transplant Jul;18(1): PMID: Immune recovery after autologous or rhg-csf primed PBSC transplantation. Rosillo MC, Ortuño F, Moraleda JM, Lozano ML, Heras I, De Arriba F, Vicente V. Eur J Haematol May;56(5): PMID: [Economic costs of autotransplantation of hematopoietic progenitors]. de Arriba F, Heras I, del Carmen Garcia M, Moraleda JM, Funes C, Ferrer F, Vicente V. Med Clin (Barc) Mar 9;106(9): Spanish. PMID: [The follow-up of the mobilization of circulating hematopoietic progenitor cells by granulocyte growth factor (G-CSF) using flow cytometry]. De Arriba F, Ortuño F, Rivera J, Heras I, Funes C, Moraleda JM, Vicente V. Med Clin (Barc) Jan 21;104(2):41-4. Spanish. PMID: Cryopreservation modifies flow-cytometric analysis of hemopoietic cells. Rosillo MC, Ortuño F, Rivera J, Moraleda JM, Vicente V. Vox Sang. 1995;68(4): PMID: Risk of thrombosis during pregnancy and post-partum in hereditary thrombophilia. Vicente V, Rodríguez C, Soto I, Fernández M, Moraleda JM. Am J Hematol Jun;46(2): No abstract available. PMID: Effect of G-CSF on the haemostatic system. Rivera J, Zuazu I, Sánchez MJ, Rosillo MC, Arribas F, Heras I, Moraleda JM, Vicente V. Thromb Haemost Jun;71(6): No abstract available. PMID: An acquired Bernard-Soulier-like platelet defect in a patient with liver cirrhosis. Sánchez Roig MJ, Rivera J, Moraleda JM, Martinez I, Vicente V. Eur J Haematol Apr;52(4): No abstract available. PMID: Quantitative defect of glycoprotein Ib in severe cirrhotic patients. Sánchez-Roig MJ, Rivera J, Moraleda JM, García VV. Am J Hematol Jan;45(1):10-5. PMID: Stability of glycoproteins Ib/IX and IIb/IIIa during preparation and storage of platelet concentrates: detection by binding assays with epitope-defined monoclonal antibodies and physiological ligands. Rivera J, Sánchez-Roig MJ, Rosillo MC, Moraleda JM, Vicente V. Vox Sang. 1994;67(2): PMID: [Crohn's disease, recurrent thrombosis, and C protein]. Zuazu Jausoro I, Salama H, Moraleda JM, Vicente García V. Med Clin (Barc) Dec 11;101(20):799. Spanish. No abstract available. PMID: Repeated infusions of DDAVP induce low response of FVIII and vwf but not of plasminogen activators European Union, Page 13 / 24

14 Vicente V, Estellés A, Laso J, Moraleda JM, Rivera J, Aznar J. Thromb Res Apr 15;70(2): PMID: [Primary thrombophilia and pregnancy]. Vicente V, Moraleda JM. Med Clin (Barc) Feb 13;100(6): Review. Spanish. No abstract available. PMID: Absence of Effect of DDAVP Infusion on Platelet Glycoprotein Ib/IX and IIb/IIIa Complexes, and their Interaction with Newly Released von Willebrand Factor. Rivera J, Roig MJ, Monteagudo J, Pereira A, Moraleda JM, Reverter JC, Vicente V. Platelets. 1993;4(4): doi: / PMID: [Bernard -Soulier syndrome]. Vicente V, Sánchez MJ, Rivera J, Moraleda JM. Sangre (Barc) Jun;37(3): Review. Spanish. No abstract available. PMID: [Hypercoagulability and exanthematous Mediterranean fever]. Vicente V, Moraleda JM, Herrero I, Ruiz R. Med Clin (Barc) Sep 28;97(10):396. Spanish. No abstract available. PMID: [Clinico-hematological characteristics of acute transformation of chronic myeloproliferative syndromes]. Hernández JM, San Miguel JF, González M, Moraleda JM, Moro MJ, Hernández J, Cuesta B, López Borrasca A. Med Clin (Barc) Sep 28;97(10): Spanish. PMID: [Hemophilia. A disappearing disease?]. Vicente V, Moraleda JM. Med Clin (Barc) Mar 30;96(12): Spanish. No abstract available. PMID: The value of the immunological subtypes and individual markers compared to classical parameters in the prognosis of acute lymphoblastic leukemia. Gómez E, San Miguel JF, González M, Orfao A, Cañizo MC, Moraleda JM, López Borrasca A. Hematol Oncol Jan-Feb;9(1): PMID: [Non-traumatic rupture of the spleen in malignant hemopathies. 2 new cases]. Moraleda JM, Vázquez ML, Vidriales MB, Hernández JM, del Cañizo C, San Miguel J. Sangre (Barc) Dec;35(6): Spanish. PMID: Surface phenotype and immunoglobulin levels in B-cell chronic lymphocytic leukaemia. Orfao A, Gonzalez M, San Miguel JF, Tomas JF, Canizo MC, Lopez-Berges MC, Moraleda JM, Lopez Borrasca A. Haematologia (Budap). 1990;23(1): PMID: [Non-Hodgkin's lymphomas. II. Prognostic factors]. San Miguel JF, Tomás JF, Martín MJ, Ríos A, Moraleda JM, Cañizo MC, González M, Nieto MJ, Sánchez J, López Borrasca A. Sangre (Barc) Oct;33(5): Spanish. No abstract available European Union, Page 14 / 24

15 PMID: [Non-Hodgkin's lymphomas. I. Clinico-biological features in a series of 98 patients]. Tomás JF, San Miguel JF, Martín MJ, Martínez R, Moraleda JM, González M, Cañizo MC, Ojeda E, Ramos F, Flores T. Sangre (Barc) Oct;33(5): Spanish. No abstract available. PMID: [Cryptosporidiosis in an AIDS patient not in any risk group]. García-Rodríguez JA, Martín Sánchez AM, Canut A, Moraleda JM. Rev Clin Esp Jan;182(1):58-9. Spanish. No abstract available. PMID: A randomized trial comparing chlorambucil plus prednisone vs cyclophosphamide, melphalan, and prednisone in the treatment of chronic lymphocytic leukemia stages B and C. Montserrat E, Alcalá A, Alonso C, Besalduch J, Moraleda JM, García-Conde J, Gutierrez M, Gomis F, Garijo J, Guzmán MC, et al. Nouv Rev Fr Hematol. 1988;30(5-6): PMID: [Plasma fibronectin in normal subjects and in Hodgkin's disease]. Moraleda JM, Batlle J, Fernanda López M, Consuelo López-Berges M, González M, San Miguel J, López Borrasca A. Sangre (Barc). 1987;32(4): Spanish. No abstract available. PMID: [Myelodysplastic syndromes: characterization of a series of 56 patients classified according to FAB criteria]. del Cañizo MC, San Miguel JF, Gascón A, Rios A, Moraleda JM, González M, Anta JP, Sánchez J, López Borrasca A. Sangre (Barc). 1987;32(4): Spanish. No abstract available. PMID: Bone marrow necrosis and treatment with interferon. Moraleda JM, Gonzalez R, Alegre A, Anta JP, San Miguel JF. J Clin Pathol Sep;39(9):1045. No abstract available. PMID: [Quantification of fibronectin in the plasma, cerebrospinal fluid and amniotic fluid by enzymoimmunoanalysis]. León VJ, León E, Moraleda JM, López-Borrasca A. Sangre (Barc). 1986;31(2): Spanish. No abstract available. PMID: Translocation (1,3) in myelodysplastic disorders. Ríos Gonzalez A, Salazar J, Moraleda JM, Del Cañizo MC. Blood Feb;65(2): No abstract available. PMID: [Sideroblastic anemia and tuberculosis]. Ríos A, Moraleda JM, del Cañizo MC, Sastre R. Med Clin (Barc) Jan 26;84(3): Spanish. No abstract available. PMID: Immunological markers of peripheral blood and lymph node lymphocytes in Hodgkin's disease. González M, Hernández F, San Miguel JF, Moraleda JM, Caballero MD, López Borrasca A. Neoplasma. 1985;32(2): PMID: [The megakaryoblastic component of mixed blast crises] European Union, Page 15 / 24

16 San Miguel JF, González M, Cañizo MC, Anta JP, Moraleda JM, Ríos A, Caballero MD, Ortega F, López Borrasca A. Sangre (Barc). 1985;30(3): Spanish. No abstract available. PMID: [Bone marrow necrosis. Apropos of 2 cases]. Alegre Amor A, González Sarmiento R, Anta García JP, Moraleda JM, Del Cañizo Fernández C, López Borrasca A. Sangre (Barc). 1985;30(4-A): Spanish. No abstract available. PMID: Biphenotypic leukemia in treated Hodgkin's disease. San Miguel JF, Gonzalez M, Moraleda JM, Alegre A, Lopez Borrasca A. J Clin Pathol Nov;37(11): No abstract available. PMID: [Danazol in idiopathic thrombopenic purpura]. González R, Alegre A, Vicente V, Moraleda JM, López Borrasca A. Med Clin (Barc) Oct 27;83(13):561. Spanish. No abstract available. PMID: [Immunologic phenotypes of acute lymphoblastic leukemias and their clinico-biological correlations]. San Miguel JF, González M, Caballero MD, Moro MJ, Prieto M, Moraleda JM, Tamagnini G, López Borrasca A. Sangre (Barc). 1984;29(5): Spanish. No abstract available. PMID: [Infections in multiple myeloma]. San Miguel J, Moraleda JM, Corrales A, Gonzalez M, Caballero L, Lopez Borrasca A. Rev Clin Esp Feb 28;168(4): Spanish. No abstract available. PMID: [DDAVP: alternative therapy in moderate pathology of Factor VIII/von Willebrand]. Vicente V, Alberca I, Moraleda JM, López Borrasca A. Sangre (Barc). 1983;28(4): Spanish. No abstract available. PMID: [Dysproteinemias in liver diseases]. Hernández F, López Berges C, León V, González M, Rodrigo M, Moraleda JM, López Borrasca A. Sangre (Barc). 1982;27(4-B): Spanish. No abstract available. PMID: [Hypogammaglobulinemia and multiple myeloma]. San Miguél J, Vicente V, Moraleda JM, Alberca I, León V, López Borrasca A. Rev Clin Esp Aug 15-31;162(3-4): Spanish. No abstract available. PMID: [Renal disease in myeloma. Role of the tumor cell mass (author's transl)]. San Miguel J, Batlle J, Alberca I, Moraleda JM, López Borrasca A. Med Clin (Barc) Apr 25;76(8): Spanish. PMID: [Electrophoretic properties of the factor VIII/vW complex in liver disease (author's transl)]. Vicente García VU, Alberca Silva I, Moraleda Jiménez JM, López Borrasca A. Sangre (Barc). 1980;25(4): Spanish. No abstract available. PMID: [Gastric juice as a means of diagnosis in gastrectomized patients with recurrent ulcer]. Rull Segura S, Picardo NG, Njenga J, Moraleda Jiménez JM, Borda Celaya F, Uribarrena Echevarria European Union, Page 16 / 24

17 R, Pons Romero F, Conchillo Teruel F. Rev Clin Esp Aug 15-31;146(3-4): Spanish. No abstract available. PMID: Projects PROJECTS (last 10 years) Title: Inmunogenotípicos studies on the classification and treatment of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) Site coordinator Organization: University Hospital Morales Meseguer. Murcia. Spain Grant: Carlos iii Institute of Health Total Funding: ,00 Proyect start and end date: Title: Neuroregenerative capacity of hematopoietic progenitor cells Organization: University Hospital Morales Meseguer. Murcia. Spain Grant: Carlos iii Institute of Health Total Funding: ,00 Proyect start and end date: Title: Cardiac regeneration in acute myocardial with bone marrow stem cells in the Region of Murcia Co- Organization: University Hospital Morales Meseguer. Murcia. Spain Grant: Seneca Foundation Total Funding: ,00 Proyect start and end date: Inmunogenotípicos studies on the classification and treatment of acute myeloid leukemia Organization: University Hospital Morales Meseguer. Murcia. Spain Grant: Carlos iii Institute of Health Total Funding: 3.570,00 Proyect start and end date: Title: "Neural potential of the hematopoietic stem cell. celular therapy study in animal models of neurodegenerative diseases Grant: Carlos iii Institute of Health Total Funding: ,00 Proyect start and end date: Title: "Phase I/II clinical study using autologous bone marrow stem cells to treat patients with amyotrophic lateral sclerosis Grant: Carlos iii Institute of Health Total Funding: ,00 Proyect start and end date: Title: Cell Therapy Trials European Union, Page 17 / 24

18 Grant: Carlos iii Institute of Health Total Funding: ,00 / year Proyect start and end date: Title: "Isolation, characterization and study of the plasticity of stem cells from amniotic membrane and dental pulp Grant: Seneca Foundation Total Funding: ,00 Proyect start and end date: Title: Implementing GMP cleanroom Grant: Ministry of Science and Innovation Total Funding: ,00 Proyect start and end date: Title: "Phase I/II clinical study using autologous bone marrow stem cells to treat patients with amyotrophic lateral sclerosis. Extension phase Grant: Ministry of Health Total Funding: ,00 Proyect start and end date: Title: "Phase II calcium phosphate porouse matrix autologous mononuclear cells seeded tissue engineering clinical trial in pseudoarthrosis (non union) patients Grant: Ministry of Health Total Funding: ,57 Proyect start and end date: Title: "Phase I/II clinical study using autologous bone marrow stem cells to treat patients with amyotrophic lateral sclerosis. Extension phase II Grant: Ministry of Health Total Funding: ,00 Proyect start and end date: Title: "Phase I/II clinical trial on the use of amniotic membrane to reepitelizate large wounds Grant: Ministry of Health Total Funding: ,00 Proyect start and end date: Title: "Bone regeneration using cell therapy and ceramic biomaterials. An alternative therapeutic Grant: CajaMurcia Foundation Total Funding: 5.600, European Union, Page 18 / 24