SASCM Laboratory Surveillance: Private Sector Jan-Dec 2013

Tamaño: px

Comenzar la demostración a partir de la página:

Download "SASCM Laboratory Surveillance: Private Sector Jan-Dec 2013"

Ignacio Navarrete Roldán
hace 7 años
Vistas:

1 SASCM Laboratory Surveillance: Private Sector Jan-Dec 2013

2 E. coli:urine n = Total of isolates ampicillin st generation cephalosporins N= nd generation cephalosporins Parenteral 3 rd generation cephalosporins gentamicin amikacin Amox / clavulanate Ciprofloxacin Levofloxacin Cotrimoxazole Ertapenem %ESBL 95 N= N= N= N= N= N= N= N=

3 E.coli: BLOODCULTURE n = Total of isolates Ampicillin Cefuroxime Ceftriaxone/cefotaxime Cefepime Amox / clavulanate Piperacillin/tazobactam gentamicin amikacin Ertapenem 99 Imipenem/meropenem/dorip enem Ciprofloxacin Tigecycline % ESBL

4 K.pneumo: BLOODCULTURES (Number of laboratories) n = Total of isolates Ampicillin Cefuroxime Ceftriaxone/cefotaxime Cefepime Amox / clavulanate Piperacillin/tazobactam Gentamicin Amikacin Ertapenem Imipenem/meropenem/dori penem Ciprofloxacin Tigecycline % ESBL N=

5 Enterobacter cloacae &SPP: BLOODCULTURES n = Total of isolates ampicillin Cefuroxime Ceftriaxone/cefotaxime Cefepime Amox / clavulanate Piperacillin/tazobactam Amikacin Gentamicin Ertapenem Imipenem/meropenem/dorip enem Ciprofloxacin Tigecycline % ESBL

6 Carbapenem Resistant Enterobacteriaceae n = Total of isolates Jhb 2 labs only Pta Dbn CT 1 lab only PE EL BFN Species Klebsiella pneumoniae Serratia marcescens Enterobacter cloacae Citrobacter freundii Escherichia coli Morganella morganii Others Genotype OXA UNABLE TO GET ACCURAT E DATA 0 94 N=16 0 VIM NDM

7 GES KPC IMP Source Urine 35 UNABLE TO GET ACCURA TE DATA UNABLE TO GET ACCURAT E DATA (1) SSTI No data No data No data No data 17 Respiratory tract Blood Intra-abdominal Other Antibiotic % susceptible Imi/mero/dori 7 UNABLE TO GET ACCURA TE DATA UNABLE TO GET ACCURAT E DATA amikacin Tigecycline 45 N=29 No data No data No data N=2 Colistin 59 No data 80 N=5

8 Positive rectal screens PCR No data No data UNABLE No data No data No data TO GET ACCURAT E DATA Culture No data No data No data No data No data

9 P. aeruginosa: BLOODCULTURES n = Total of isolates Ceftazidime Cefepime Pip/tazobactam Gentamicin Amikacin Tobramycin Meropenem Imipenem Doripenem Ciprofloxacin Polymyxin (Colistin) (N=13) 75 Aztreonam 45 N= N=6

10 Acinetobacter baumannii: BLOODCULTURES n = Total of isolates Ceftazidime Cefepime Pip/tazobactam Gentamicin Amikacin Tobramycin Meropenem Imipenem Doripenem Ciprofloxacin Polymyxin (Colistin) (N=6) Cotrimoxazole 29 N= Tigecycline 79 (N=144)

11 S. aureus: BLOODCULTURES n = Total of isolates Cloxacillin Cotrimoxazole Erythromycin Clindamycin Fusidic acid Rifampicin Gentamicin Teicoplanin Vancomycin Linezolid Daptomycin

12 E. faecalis: BLOODCULTURES n = Total of isolates Ampicillin Gentamicin 35 N= Teicoplanin 99 Vancomycin 99 Linezolid Daptomycin N=7 N=9 70

13 E. faecium: BLOODCULTURES n = Total of isolates Ampicillin Gentamicin Teicoplanin Vancomycin Linezolid Daptomycin

14 C. albicans: BLOODCULTURES No of isolates a Fluconazole Voriconazole Posaconazole Amphotericin B *Caspofungin Anidulafungin (N=62) a Candida albicans isolates that were fluconazole resistant may have had trailing end-points and not elevated MICs

15 Candida Non-Albicans: BLOODCULTURES Candida parapsilosis Number of Isolates Fluconazole Voriconazole Posaconazole Amphotericin B *Caspofungin Anidulafungin (N=92) Candida glabrata Number of Isolates Fluconazole Voriconazole Posaconazole Amphotericin B *Caspofungin

16 Anidulafungin (N=23) Candida krusei Number of Isolates Fluconazole Voriconazole Posaconazole Amphotericin B *Caspofungin Anidulafungin Candida tropicalis Number of Isolates Fluconazole Voriconazole Posaconazole Amphotericin B *Caspofungin 89 89

17 Anidulafungin (N=1) Candida species Number of Isolates Fluconazole Voriconazole Posaconazole Amphotericin B *Caspofungin Anidulafungin *Caspofungin MIC s may not be reliable and resistance was not confirmed by testing another agent (e.g. anidulafungin) or by fks gene sequencing NB. One of the Cape Town centres did not send candida data as per species type and these are therefore all classified as Candida spp (n=42)

18 S. pneumoniae: LRTI n = Total number of isolates Penicillin~ </= Telithromycin - susceptible Erythromycin susceptible rd generation cephalosporins (parenteral)* Susceptible IR HR Quinolones Levo (N=59) 99 Moxi 98 ~Penicillin breakpoints (oral): CLSI S</=0.06 IR HR >/=2 ~ Penicillin breakpoints (parenteral non-meningitis): CLSI S</=2 IR 4 HR >/=8 * 3 rd Cephalosporins (non-meningitis): CLSI S</=1 IR 2 HR >/=4 : Not tested

19 Haemophilus influenza: RTI No of isolates Ampicillin B-lactamase positive (N=232)

Documentos relacionados

EPINE: EVOLUCIÓN , CON RESUMEN DE 2014

EPINE: EVOLUCIÓN , CON RESUMEN DE 2014 EPINE: EVOLUCIÓN 1990-2014, CON RESUMEN DE 2014 Hospitales incluidos. EPINE 1990-2014 Número de Hospitales 300 250 258 257 253 266 276 278 287 287 271 282 269 200 201 206 214 224 233 243 243 246 241 186