Alejandro Omar Blenkmann

Transcripción

1 Alejandro Omar Blenkmann Postdoctoral Fellow CONICET Investigation topic: Localization and characterization of brain activity sources Summary: My interest is to characterize neuronal networks involved in normal and pathological human brain function. I study signals from scalp electroencephalography (EEG), as well as intracranial recordings (ieeg), magnetic resonance imaging (MRI) and single cell recordings. Different algorithms and models are proposed to localize and characterize of neuronal populations involved in: i) cognitive processing of information and ii) in abnormal electrical activity in patients with epilepsy. Institutions: Laboratory of Clinical Neurocience: Epilepsy and Cognition, Institute of Cell Biology and Neuroscience (IBCN) "Prof. E. de Robertis", School of Medicine, University of Buenos Aires - CONICET. Epilepsy Section, Division of Neurology Ramos Mejia Hospital, Buenos Aires. Collaborator at Laboratory of Industrial Electronics, Control and Instrumentation (LEICI), Faculty of Engineering, National University of La Plata. Teaching experience Associate professor Department of Information Technology, Favaloro University. Period: June present. Simple dedication. Signal, Systems and Circuits, undergraduate course. Course of the 4th Digital Signal Processing, undergraduate course. Course of the 7th Assistant professor Department of Electronics, Buenos Aires Regional Faculty, National Technological University. Period: July present. Simple dedication. Linear Systems Analysis, undergraduate course. Course of the 4th and 5th semester of Electronic Engineering. 1 Alejandro Blenkmann January 2013

2 Chief of Practical Applications (Jefe de Trabajos Prácticos - JTP) Department of Information Technology, Favaloro University. Period: March 2009 June Simple dedication. Signal, Systems and Circuits, undergraduate course. Course of the 4th Digital Signal Processing, undergraduate course. Course of the 7th Education PhD. in Engineer at National University of La Plata, Argentina. Supervisors: Silvia Kochen and Carlos Muravchik. Topic: Localization of Brain Activity Sources Biomedical Engineer at Favaloro University, Buenos Aires, Argentina. Graduated with honors Bachelor in Engineering Sciences, Favaloro University, Buenos Aires, Argentina. Graduated with honors Electronic Technician, Comahue Technological Institute, Neuquén, Argentina Grants and Fellowships National Council of Scientific and Technical Investigations (CONICET), Argentina. Post doctoral fellowship, April 2012 March National Council of Scientific and Technical Investigations (CONICET), Argentina. PhD fellowship, Type II. April 2010 March Balseiro Institute (CNEA) International Brain Research Organization (IBRO). Travel grant to attend the course Modeling in Neuroscience at J.A. Balseiro School October International League Against Epilepsy (ILAE). Travel grant to attend at the Latin-American Summer School on Epilepsy II. February National Council of Scientific and Technical Investigations (CONICET), Argentina. PhD fellowship, Type I. September March Agustín de Betancourt Foundation (Spain), research grant and Polytechnic University of Madrid, Spain, undergraduate student grant to make a short-term visit of 3 months at the Material Science Department of the Polytechnic University of Madrid. Topic: Mechanic Characterization of biomaterials. March - June Alejandro Blenkmann January 2013

3 Peer-reviewed Publications 1. IBAÑEZ AGUSTIN; CARDONA JUAN; VIDAL DOS SANTOS YAMIL; BLENKMANN ALEJANDRO; ARAVENA PIA; ROCA MARIA; HURTADO ESTEBAN; NERGUIZIAN MIRNA; AMORUSO LUCIA; GOMZ-AREVALO GONZALO; CHADE ANABEL; DUBROVSKY ALBERTO; GERSHANIK OSCAR; KOCHEN SILVIA; GLENBERG ARTHUR; MANES FACUNDO; BEKINSCHTEIN TRISTAN. Motor-language coupling: Direct evidence from early Parkinsons disease and intracranial cortical recordings. CORTEX En prensa. 2. SEIFER GUSTAVO; BLENKMANN ALEJANDRO; PRINCICH JUAN PABLO; CONSALVO DAMIAN; PAPAYANNIS CRISTINA; MURAVCHIK CARLOS; KOCHEN SILVIA. Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features. Epilepsy Research and Treatment p PRINCICH JUAN PABLO; CONSALVO DAMIAN; KAUFMAN MARCELO; SEIFER GUSTAVO; BLENKMANN ALEJANDRO; KOCHEN SILVIA. Contribution of diffusion tensor magnetic resonance imaging to the diagnosis of focal cortical dysplasias. REVISTA DE NEUROLOGIA vol.54 n. p IBAÑEZ AGUSTIN; URQUINA HUGO; PETRONI AGUSTIN; BAEZ SANDRA; LOPEZ VLADRIMIR; DO NASCIMIENTO MICAELA; HERRERA EDUAR; GUEX RAFAEL; HURTADO ESTEBAN; BLENKMANN ALEJANDRO; BELTRACHINI LEANDRO; GELORMINI CARLOS; SIGMAN MARIANO; LISCHINSKY ALICIA; TORRALVA TERESA; TORRENTE FERNANDO; CETKOVICH MARCELO; MANES FACUNDO. Neural Processing of Emotional Facial and Semantic Expressions in Euthymic Bipolar Disorder (BD) and Its Association with Theory of Mind (ToM). PLOS ONE.San Francisco: PUBLIC LIBRARY SCIENCE vol.7 n. p PETRONI AGUSTIN; CANALES-JOHNSON ANDRÉS; URQUINA HUGO; GUEX RAFAEL; URTADO ESTEBAN; BLENKMANN ALEJANDRO; VON ELLENRIEDER NICOLÁS; MANES FACUNDO; SIGMAN MARIANO; IBAÑEZ AGUSTIN. The cortical processing of facial emotional expression is associated with social cognition skills and executive functioning: A preliminary study. NEUROSCIENCE LETTERS vol. 505 n 1. p BLENKMANN ALEJANDRO; SEIFER GUSTAVO; PRINCICH JUAN PABLO; CONSALVO DAMIAN; KOCHEN SILVIA; MURAVCHIK CARLOS. Association between equivalent current dipole source localization and focal cortical dysplasia in epilepsy patients. EPILEPSY RESEARCH vol.98 n. p IBAÑEZ AGUSTIN; PETRONI AGUSTIN ; URQUINA HUGO; TORRENTE FERNANDO; TORRALVA TERESA; URTADO ESTEBAN; GUEX RAFAEL; BLENKMANN ALEJANDRO; BELTRACHINI LEANDRO; MURAVCHIK CARLOS; BAEZ SANDRA; CETKOVICH MARCELO; SIGMAN MARIANO; LISCHINSKY ALICIA; MANES FACUNDO. Cortical deficits of emotional face processing in adults with ADHD: Its relation to social cognition and executive function. SOCIAL NEUROSCIENCE vol.6 n. p BELTRACHINI LEANDRO; BLENKMANN ALEJANDRO; VON ELLENRIEDER NICOLÁS; PETRONI AGUSTIN; URQUINA HUGO; MANES FACUNDO; IBAÑEZ AGUSTIN; MURAVCHIK CARLOS. Impact of head models in N170 component source imaging: results in control subjects and ADHD patients. JOURNAL OF PHYSICS: CONFERENCE SERIES. 8th Argentinean Bioengineering Society Conference (SABI 2011) and 7th Clinical Engineering Meeting;.: IOPscience vol.332 n 1. p1-10. issn Alejandro Blenkmann January 2013

4 Book Chapters 1. IBAÑEZ AGUSTIN; PETRONI AGUSTIN; URQUINA HUGO; TORRALVA TERESA; BLENKMANN ALEJANDRO; BELTRACHINI LEANDRO; MURAVCHIK CARLOS; BAEZ SANDRA; CETKOVICH MARCELO; TORRENTE FERNANDO; HURTADO ESTEBAN; GUEX RAFAEL; SIGMAN MARIANO; LISCHINSKY ALICIA; MANES FACUNDO. Cortical deficits in emotion processing for faces in adults with ADHD: Its relation to social cognition and executive functioning. Capítulo publicado en Social Neuroscience of Psychiatric Disorders. Londres: PSYCHOLOGY PRESS ISBN Peer-reviewed Conference Proceedings 1. BLENKMANN ALEJANDRO; BELTRACHINI LEANDRO; PRINCICH JUAN PABLO; MURAVCHIK CARLOS; KOCHEN SILVIA. Evaluation of source localization algorithms from eeg intracranial recordings simulated with physiologically plausible neuronal populations model. Ecuador. Quito Libro. Resumen. Congreso. VII Congreso Latinoamericano de Epilepsia. International League Against Epilepsy 2. BELTRACHINI LEANDRO; BLENKMANN ALEJANDRO; VON ELLENRIEDER NICOLÁS; PETRONI AGUSTIN; URQUINA HUGO; MANES FACUNDO; IBAÑEZ AGUSTIN; MURAVCHIK CARLOS. Impact of head models in N170 component source imaging: results in control subjects and ADHD patients. Argentina. Mar del Plata XVIII Congreso Argentino de Bioingenieria. Sociedad Argentina de Bioingenieria 2. BLENKMANN ALEJANDRO; BELTRACHINI LEANDRO; VON ELLENRIEDER NICOLÁS; KOCHEN SILVIA; MURAVCHIK CARLOS. Evaluación de sloreta para la resolución del problema inverso en o o ECoG utilizando modelos de poblaciones neuronales fisiológicamente plausibles. Argentina. Paraná Congreso. XIV Reunión de trabajo en Procesamiento de la información y Control. 3. BLENKMANN ALEJANDRO; SEIFER GUSTAVO; PRINCICH JUAN PABLO; CONSALVO DAMIAN; KOCHEN SILVIA; MURAVCHIK CARLOS. Método de localización semiautomática de electrodos intracraneales a partir de imágenes de TAC y RM. Argentina. Mar del Plata XLVII Congreso Argentino de Neurología. Sociedad Neurológica Argentina 4. PRINCICH JUAN PABLO; WASSERMANN DEMIAN; SEIFER GUSTAVO; BLENKMANN ALEJANDRO; CONSALVO DAMIAN; KOCHEN SILVIA. Detectar y Cuantificar Automáticamente las Alteraciones de la Sustancia Blanca Asociadas a las D.C.F.. Argentina. Mar del Plata XLVII Congreso Argentino de Neurología. Sociedad Neurológica Argentina 5. PRINCICH JUAN PABLO; SEIFER GUSTAVO; BLENKMANN ALEJANDRO; CONSALVO DAMIAN; KOCHEN SILVIA. Reorganización de la sustancia blanca distal a las Displasias Corticales Focales (DCF) en pacientes con epilepsia refractaria detectada a través de Imágenes por Tensor de Difusión (ITD) en Resonancia Magnética (RM). Colombia. Cartagena Congreso. 6to Congreso Latinoamericano de Epilepsia. International League Against Epilepsy 6. BLENKMANN ALEJANDRO; VON ELLENRIEDER NICOLÁS; SEIFER GUSTAVO; PRINCICH JUAN PABLO; KOCHEN SILVIA; MURAVCHIK CARLOS. Algoritmo MUSIC para la localización de fuentes de actividad cerebral. Simulaciones y ejemplos. Argentina. Paraná, XVII Congreso Argentino de Bioingeniería, SABI' 09. Sociedad Argentina de Bioingenieria 4 Alejandro Blenkmann January 2013

5 7. VON ELLENRIEDER NICOLÁS; BELTRACHINI LEANDRO; BLENKMANN ALEJANDRO; SAN MARTIN JUAN PABLO; KOCHEN SILVIA; MURAVCHIK CARLOS. Determinación de la ubicación de electrodos de EEG basada en fotografías digitales. Argentina. Buenos Aires XIII Reunión de Trabajo en Procesamiento de la Información y Control. Reunión de Trabajo en Procesamiento de la Información y Control 8. SEIFER GUSTAVO; BLENKMANN ALEJANDRO; CONSALVO DAMIAN; PRINCICH JUAN PABLO; MURAVCHIK CARLOS; KOCHEN SILVIA. LOCALIZACIÓN DE FUENTE EPILEPTOGENA EN UN PACIENTE CON ESCLEROSIS HIPOCAMPAL Y PATOLOGIA DUAL. Argentina. Mar del Plata XLVI Congreso Argentino de Neurología. Sociedad Neurológica Argentina 9. BLENKMANN ALEJANDRO; SEIFER GUSTAVO; PAPAYANNIS CRISTINA; CONSALVO DAMIAN; SILVA W.ALTER; MURAVCHIK CARLOS; KOCHEN SILVIA. Localización de focos epileptógenos utilizando el método de dipolo equivalente de corriente (ECD) en pacientes con epilepsia y malformaciones del desarrollo cortical (MCD). Uruguay. Montevideo to Congreso Latinoamericano de Epilepsia. International League Against Epilepsy 10. SEIFER GUSTAVO; BLENKMANN ALEJANDRO; CONSALVO DAMIAN; SILVA WALTER; MURAVCHIK CARLOS; KOCHEN SILVIA. Determinación del área cortical necesaria para la visualización de la actividad interictal en el registro de scalp en un paciente con displasia cortical focal. Argentina. Mar del Plata XLV Congreso Argentino de Neurología. Sociedad Neurológica Argentina 11. PRINCICH JUAN PABLO; CONSALVO DAMIAN; SEIFER GUSTAVO; BLENKMANN ALEJANDRO; ODDO SILVIA; SOLIS PATRICIA; LOMLOMDJIAN CAROLINA; ELETA MARTIN; KOCHEN SILVIA. Utilidad de las Imágenes por Tensor de Difusión (ITD) en las Displasias Corticales Focales.. Uruguay. Montevideo Congreso. 5to Congreso Latinoamericano de Epilepsia. International League Against Epilepsy 12. PRINCICH JUAN PABLO; SEIFER GUSTAVO; BLENKMANN ALEJANDRO; CONSALVO DAMIAN; KOCHEN SILVIA. Reorganización de la sustancia blanca distal a las Displasias Corticales Focales (DCF) en pacientes con epilepsia refractaria detectada a través de Imágenes por Tensor de Difusión (ITD) en Resonancia Magnética (RM). Argentina. Revista Argentina de Neurología XLVI Congreso Argentino de Neurología. Sociedad Neurológica Argentina 13. BENÍTEZ MATÍAS; BLENKMANN ALEJANDRO; CANO RAMIRO; RAPACIOLI MELINA; FLORES VLADIMIR. Implementacion de algoritmos basicos para el analisis de la proliferacion celular diferencial. Argentina. Paraná XV Congreso Argentino de Bioingeniería (SABI 2005). Sociedad Argentina de Bioingenieria Jury of undergraduate thesis Title: T-BESP: Tools for bioelectrical signal processing. Member of the evaluation committee of "Final year project", Biomedical Engineering, Favaloro University. Students: Mirna Nerguizian and Facundo Doval. September Final year project direction Title: Effective connectivity in focal cortical dysplasias Student: Mauro Pieretto. Career; Biomedical engineering, Favaloro University. Director: Alejandro Blenkmann. April 2012 Present. Title: Human single cell recordings proccesing. Student: Bruno Alvarez, Career: Biomedical engineering, Favaloro University. Director: Alejandro Blenkmann. April Present. 5 Alejandro Blenkmann January 2013

6 Implementation of a Disease Registry service in the Epilepsy Center at Ramos Mejía Hospital. Student: Soledad Reyes. Career: Biomedical engineering, Favaloro University. Director: D. Luna, Co-Directors: S. Kochen and A. Blenkmann. November Qualification awarded: 10. Student internship supervition Single cell recordings and intracranial Event Related Potentials (ERP) in humans. Student: Martin Sapir. Career: Biomedical engineering, Favaloro University. Director: A. Blenkmann, Co-Director: S. Kochen. December present. Event Related Potentials (ERP) from intracranial electrocorticography (ECoG). Student: Florence Jacobacci. Career: Biomedical engineering, Favaloro University. Director: A. Blenkmann, Co-Director: A. Ibanez. June to December 2012 Event Related Potentials (ERP) from intracranial electrocorticography (ECoG). Student: Mirna Nerguizian. Career: Biomedical engineering, Favaloro University. Director: A. Ibanez. Co-Director: A. Blenkmann, September- December Undergraduate Research Experience Short stay in the Department of Materials Science, Faculty of Civil Engineering and Ports, Polytechnic University of Madrid. Topic: "Mechanical characterization of biomaterials." Period: March to June Language Spanish: native language. English: Test of English as a Foreign Language (TOEFL), USA. Rating: 210 over 300. Year Alejandro Blenkmann January 2013