Curriculum vitae Standardized form

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1 Curriculum vitae Standardized form Total number of pages: 12 Name: Cristina Esteva Font Date: 01/23/2012

2 PERSONAL DATA Family name: Esteva Font Forename: Cristina ID/Passport no: R Date of birth : 11/01/1979 Gender: Female Nacionality: Spain PRESENT PROFESIONAL POSITION Institution: University of California San Francisco (UCSF) Faculty, School or Institute: Laboratory for Cell and Membrane Biophysics Department: Department of Medicine, Division of Nephrology Address: 505 Parnassus Avenue, HSE-1246 San Francisco, CA Country: United States of America Telephone (indicate prefix, number and extension): +1(415) Fax: crisesteva@hotmail.com Field of study (UNESCO codes): 2403 Profesional status: Post doc Start date: 01/31/12 Administrative status Permanent Staff Hired on contracts Acting X Fellowship holder Others specify: Full-time Part-time X PhD: Cellular and Moleular Biology Thesis title: Study of sodium transporters and renal aquaporins on water imbalance disorders. Center: Universitat Autònoma de Barcelona Date: 2008 Supervisors: Patricia Fernandez-Llama and Elisabet Ars Criach PRESENT RESEARCH AREA Aquaporin-dependent cell migration and proliferation in cancer ACADEMIC BACKGROUND Bachelor Centre Date Biology University of Barcelona 2003 Ph.D. Centre Thesis Supervisor Date Cellular Biology Universitat Barcelona Autònoma Patricia Llama Fernández 2008

3 PAST SCIENTIFIC EXPERIENCE (*) Position R&D Centre Institution (**) Start date End date Cancer biochemistry lab Assistant professor and Biology Department University of Girona post doc Girona, Spain 12/01/08 01/30/12 The Water and Salt Research Center, Guest PhD Institute of Anatomy, University of Aarhus 07/01/08 09/30/08 University of Aarhus, Aarhus, Denmark PhD student PhD student Work experience Laboratorio de Biología Molecular, Fundació Puigvert, Barcelona, Spain The Water and Salt Research Center, Institute of Anatomy, University of Aarhus, Aarhus, Denmark Institut Municipal d Investigacions Biomèdiques I.M.I.M), Barcelona, Spain Universitat Autònoma de Barcelona Fundació Puigvert 07/ /2008 University of Aarhus 05/ /2007 Institut Municipal d Investigacions Biomèdiques I.M.I.M), Barcelona, Spain 09/ /2002 (*) The information contained in this chart will be used to verify the placement requirements with respect to mobility. (**) If the Institution is a joint centre, you should specify all the centres involved in running it. LANGUAGES (N = NORMAL, G = GOOD, P = PERFECTLY) Language Speaking Reading Writing Catalan P P P Spanish P P P English P P P

4 TEACHING ACTIVITY Academic courses From 2011 To: 2012 Subject title: Experimental Biochemistry Credits/ hours (ECTS): 3 From September To January Academic courses From 2011 To: 2012 Subject title: Biochemistry Credits/ hours (ECTS): 6 From September To January Academic courses From 2010 To: 2011 Subject title: Experimental Biochemistry Credits/ hours (ECTS): 3 From September To January Academic courses From 2010 To: 2011 Subject title: Biochemistry Credits/ hours (ECTS): 6 From September To January Academic courses From 2009 To: 2010 Subject title: Integrated Scientific Techniques III Credits/ hours (ECTS): 6 From February To June Academic courses From 2009 To: 2010 Subject title: Biochemistry Credits/ hours (ECTS): 7,5 From February To June Academic courses From 2009 To: 2010 Subject title: Enzymology Credits/ hours (ECTS): 7 From September To: December

5 PARTICIPATION IN RESEARCH PROJECTS PROJECT TITLE: Fisiopatología molecular de la hipertensión arterial inducida por los inhibidores de la calcineurina. Estudio de la expresión génica y proteica de los transportadores renales de sodio en un modelo experimental de hipertensión arterial inducida por ciclosporina FINANCIAL ENTITY: Fundació Marató de TV3 LENGHT FROM:2001 TO: 2003 PRINCIPAL INVESTIGATOR: Patricia Fernandez Llama PROJECT TITLE: Estudio de la excreción de los transportadores renales de sodio y la respuesta presora a la ingesta de sal en pacientes hipertensos FINANCIAL ENTITY: Fondo de Investigación sanitaria LENGHT FROM:2003 TO: 2005 PRINCIPAL INVESTIGATOR: Patricia Fernandez Llama PROJECT TITLE: Role of the aquaporins in hepatic cirrhosis FINANCIAL ENTITY: Fondo de Investigación sanitaria LENGHT FROM:2004 TO: 2006 PRINCIPAL INVESTIGATOR: Patricia Fernandez Llama PROJECT TITLE:Fisiopatología molecular de la enuresis nocturna monosimptomática. Juegan la aquaporina-1 y el cotransportador de sodio NKCC2 un papel en el defecto de la concentración urinaria. FINANCIAL ENTITY: Fondo de Investigación sanitaria LENGHT FROM:2005 TO: /2007 PRINCIPAL INVESTIGATOR: Patricia Fernandez Llama PROJECT TITLE: Exosomes excretion FINANCIAL ENTITY: European Union LENGHT FROM:05/2007 TO: 10/2007 PRINCIPAL INVESTIGATOR: Soren Nielsen PROJECT TITLE: Grups de recerca consolidats (grupos de investigación consolidados) FINANCIAL ENTITY: DGR (Dirección General de Investigación de la Generalitat de Catalunya). N/r: 2009SGR717 LENGHT FROM:2009 TO: /2014 PRINCIPAL INVESTIGATOR: Rafael de Llorens

6 PUBLICATIONS Key: B= full book, CB.= chapter of book, A= article, R= review, E= editor (*) Those publications in process and not yet published, just specify publication status. (**)When applicable/available AUTHORS (in order of authorship): Esteva-Font C, Ballarín JA, Fernández-Llama P. TITLE: Molecular biology of water and salt regulation in the kidney. JOURNAL/BOOK TITLE: Cell Mol Life Sci KEY: R DATE OF PUBLICATION (*): 2011 JOURNAL WITHIN THE 25% HIGHER IMPACT FACTOR IN ITS KNOWLEDGE AREA AT THE YEAR OF PUBLICATION (**): YES NO IMPACT FACTOR (**): TOTAL NUMBER OF TIMES CITED: AUTHORS (in order of authorship): Esteva-Font C, Wang X, Ars E, Guillén-Gómez E, Sans L, González Saavedra I, Torres F, Torra R, Masilamani S, Ballarín JA, Fernández-Llama P. TITLE: Are sodium transporters in urinary exosomes reliable markers of tubular sodium reabsorption in hypertensive patients? JOURNAL/BOOK TITLE: Nephron Physiol KEY: A DATE OF PUBLICATION (*): 2010 JOURNAL WITHIN THE 25% HIGHER IMPACT FACTOR IN ITS KNOWLEDGE AREA AT THE YEAR OF PUBLICATION (**): YES NO IMPACT FACTOR (**): TOTAL NUMBER OF TIMES CITED: AUTHORS (in order of authorship): Esteva-Font C, Torra R, Fernández-Llama P. TITLE: Sodium transporters and aquaporins: Future renal biomarkers? JOURNAL/BOOK TITLE: revista: Med Clin-Barcelona KEY: R DATE OF PUBLICATION (*): 2007 JOURNAL WITHIN THE 25% HIGHER IMPACT FACTOR IN ITS KNOWLEDGE AREA AT THE YEAR OF PUBLICATION (**): YES NO X IMPACT FACTOR (**): TOTAL NUMBER OF TIMES CITED: AUTHORS (in order of authorship): Esteva-Font C, Ars E, Guillén-Gómez E, Campistol J.M, Sans L, Jiménez W, Knepper M.A, Torres F, Torra R, Ballarín J.A, Fernández-Llama P. TITLE: Cyclosporine-induced hypertension is associated with increased sodium transporter of the loop of Henle (NKCC2)

7 JOURNAL/BOOK TITLE: Nephrol Dial Transplant KEY: A DATE OF PUBLICATION (*): 2007 JOURNAL WITHIN THE 25% HIGHER IMPACT FACTOR IN ITS KNOWLEDGE AREA AT THE YEAR OF PUBLICATION (**): YES X NO IMPACT FACTOR (**): TOTAL NUMBER OF TIMES CITED: AUTHORS (in order of authorship): Esteva-Font C, Guevara M, Baccaro M.E, Ars E, Jiménez W, Arroyo V, Ballarín J.A, Ginès P, Fernández-Llama P. TITLE: Aquaporin-1 and aquaporin-2 urinary excretion in cirrhosis. relationship with ascites and hepatorenal síndrome JOURNAL/BOOK TITLE: Hepatology KEY: A DATE OF PUBLICATION (*): 2006 JOURNAL WITHIN THE 25% HIGHER IMPACT FACTOR IN ITS KNOWLEDGE AREA AT THE YEAR OF PUBLICATION (**): YES X NO IMPACT FACTOR (**): TOTAL NUMBER OF TIMES CITED: AUTHORS (in order of authorship) Fernández-Llama P, Ageloff S, Fernández-Varo G, Ros J, Wang X, Garra N, Esteva-Font C, Ballarín J, Barcelo P, Arroyo V, Stokes J.B, Knepper M.A, Jiménez W. TITLE: Sodium Retention in Cirrhotic Rats is Associated with Increased Renal Abundances of Sodium Transporter Proteins JOURNAL/BOOK TITLE: Kidney int KEY: A DATE OF PUBLICATION (*): 2005 JOURNAL WITHIN THE 25% HIGHER IMPACT FACTOR IN ITS KNOWLEDGE AREA AT THE YEAR OF PUBLICATION (**): YES X NO IMPACT FACTOR (**): TOTAL NUMBER OF TIMES CITED:

8 PARTICIPATION IN RESEARCH CONTRACTS OF SPECIAL RELEVANCE WITH COMPANIES AND/OR PRIVATE OR PUBLIC FUNDING BODIES CONTRACT TITLE: Clonación de proteínas de interés diagnóstico y terapéutico. FINANCIAL ENTITIES: Roche-Diagnostics SL. LENGHT FROM:2003 TO: Present PRINCIPAL INVESTIGATOR: Dr. Rafael de Llorens and Dr. Núria Aleixandre

9 STAYS IN INTERNATIONALLY RECOGNIZED CENTRES KEY: D=Ph.D student, P=postdoctoral. G= guest, S=staff, O=others (specify) CENTRE: The Water and Salt Research Center, Institute of Anatomy, University of Aarhus PLACE: Aarhus COUNTRY: Denmark YEAR: 2008 LENGHT: 3 months TOPIC: Subcellular localization of aquaporins and renal sodium transporters KEY: P CENTRE: The Water and Salt Research Center, Institute of Anatomy, University of Aarhus PLACE: Aarhus COUNTRY: Denmark YEAR: 2007 LENGHT: 6 months TOPIC: Urinary excretion of exosomes KEY: D

10 PRESENTATIONS IN CONGRESSES AUTHORS: Cristina Esteva-Font, Søren Nielsen, Jørgen Frøkiær TITLE: Urinary Excretion of Renal Sodium Transporters and Aquaporins. Exosomal way. TYPE OF PRESENTATION: Oral presentation CONGRESS: Meeting on Aquaglyceroporins PUBLICATION: MEETING PLACE: Barcelona, SPAIN YEAR: 2007 AUTHORS: C. Esteva-Font, I. González Saavedra, E. Ars Criach, L. Sans Atxer, J. Ballarin Castan, P. Fernández-Llama TITLE: Excreción Urinaria de las Proteínas Transportadoras de Sodio (NKCC2 and NCC) en Hipertensos Sal-sensibles y sal-resistentes TYPE OF PRESENTATION: Poster CONGRESS: 12a Reunión Nacional de la Sociedad Española de Hipertensión, Liga Española para la Lucha contra la Hipertensión Arterial PUBLICATION: MEETING PLACE: Sevilla, SPAIN YEAR: 2007 AUTHORS: C. Esteva-Font, P. Fernández-Llama. TITLE: Hipertensión Arterial y Transportadores Renales de Sodio TYPE OF PRESENTATION: Oral presentation CONGRESS: Reunión de jovenes investigadores en hipertensión arterial. PUBLICATION: MEETING PLACE: Cardona, SPAIN YEAR: 2007 AUTHORS: C. Esteva-Font, M. Guevara, M.E. Baccaro, E. Ars, W. Jiménez, V. Arroyo, J.A. Ballarín, P. Ginès, P. Fernández-Llama TITLE: Disminución de la excreción urinaria de aquaporinas en pacientes con cirrosis hepática descompensada TYPE OF PRESENTATION: poster CONGRESS: Reunión anual de la Sociedad Española de Nefrología PUBLICATION: MEETING PLACE: Malaga, SPAIN YEAR: 2005 AUTHORS: P. Fernández-Llama, C. Esteva-Font, M. Guevara, M.E. Baccaro, E. Ars, W. Jiménez, V. Arroyo, J.A. Ballarín, P. Ginés TITLE: Decreased Urinary Excretion of Aquaporin -1 and Aquaporin-2 in Patients with Decompensated Liver Cirrhosis TYPE OF PRESENTATION: Poster CONGRESS: International conference on aquaporins PUBLICATION: Hepatology 2006 MEETING PLACE: Brussels, BELGIUM YEAR: 2005 AUTHORS: Cristina Esteva-Font, Elisabet Ars, Josep M. Campistol, Wladimiro Jimenez, Mark A. Knepper, Jose A. Ballarin, Pedro Barceló, Patricia Fernández-Llama

11 TITLE: Cyclosporine - Induced Hypertension Is Associated with Increased Sodium Transporter of the Loop of Henle (NKCC2/BSC1) TYPE OF PRESENTATION: Poster CONGRESS: XLII European Renal Association European Dialysis and Transplant Association (ERA- EDTA) Congress PUBLICATION: Nephrol Dial Transplant MEETING PLACE: Istanbul, TURKEY YEAR: 2005 AUTHORS: C. Esteva-Font, E. Ars Criach, J.M. Campistol Plana, W. Jimenez Povedano, M.A. Knepper, J.A. Ballarin Castan, P. Barceló Reverter, P. Fernández-Llama. TITLE: La Hipertensión Arterial Inducida por Ciclosporina se Asocia con un Incremento del Transportador Renal de Sodio del Asa de Henle (NKCC2) TYPE OF PRESENTATION: Oral presentation CONGRESS: 10a Reunión Nacional de la Sociedad Española de Hipertensión, Liga Española para la Lucha contra la Hipertensión Arterial PUBLICATION: Nephrol Dial Transplant MEETING PLACE: Barcelona, SPAIN YEAR: 2005 AUTHORS: C. Esteva-Font, E. Ars, J.M. Campistol, W. Jiménez, M.A. Knepper, J.A. Ballarín, P. Barceló, P. Fernández-Llama. TITLE: El Aumento de la Presión Arterial Inducida por Ciclosporina se Asocia a un Incremento del Transportador Renal de Sodio del asa de Henle (NKCC2) TYPE OF PRESENTATION: Oral presentation CONGRESS: Reunión Anual de la Sociedad Catalana de Nefrología (SCN) PUBLICATION: Nephrol Dial Transplant MEETING PLACE: Barcelona, SPAIN YEAR: 2004

12 OTHER ACHIEVEMENTS (in one DIN A4 page only) Award to: Investigación Clínica, XIX Edición del Premio a la Investigación Clínica en Nefrología, Fundación Renal Inigo Álvarez de Toledo. ESPAÑA (2007) Póster awarded, 12a Reunión Nacional de la Sociedad Española de Hipertensión, Liga Española para la Lucha contra la Hipertensión Arterial. Sevilla, ESPAÑA (2007)