Termination of an agreement to act in concert 15 +

Transcripción

1 FORM TR1 BE PART I 1) Status of the notification Final 2) Issuer Name TIGENIX Identification number ) Reason for the notification Termination of an agreement to act in concert 15 4) Notification by Persons acting in concert who have concluded an agreement to hold, acquire or dispose of voting 6 5) Persons subject to the notification requirement Name (& legal form for legal persons) Address (for legal persons) Genetrix S.L. Plaza de la Encina, nº 111, núcleo 1, planta 3ª, CP 2876 Tres Cantos (Madrid, Spain Genetrix Life Sciences A.B. Kungängsgatan 1719, Uppsala (Sweden) Pilar Matji Tuduri Arequipa, 15a planta, 2843 Madrid, Spain Miguelina Matji Tuduri Arequipa, 15a planta, 2843 Madrid, Spain Manuel Matji Tuduri Arequipa, 15a planta, 2843 Madrid, Spain María José Lafita Torres Fortuny 37, 281 Madrid, Spain María Ángeles Lafita Torres Fortuny 37, 281 Madrid, Spain Elena Lafita Torres Fortuny 37, 281 Madrid, Spain Lucía Lafita Torres Fortuny 37, 281 Madrid, Spain Alfredo Lafita Torres Fortuny 37, 281 Madrid, Spain Alfredo Lafita Pardo Fortuny 37, 281 Madrid, Spain Emilia Torres Rojas Fortuny 37, 281 Madrid, Spain Surfolk SL Fortuny 37, 281 Madrid, Spain Jorge Alemany Herrera San Miguel 7, 2822 Madrid, Spain José Antonio Matji Tuduri Baruma, C/ Arequipa, 15a planta 2843 Madrid, Spain Nerel S.L. Baruma, C/ Arequipa, 15a planta 2843 Madrid, Spain Ventech S.A. Rue de montessuy 57, 757 Paris LSP III Management B.V. Johannes Vermeerplein 9, 171 DV Amsterdam, Netherlands Ysios Capital Partners S.G.E.C.R. Calle Baldiri Reixach 112, 828 Barcelona, Spain Biopartners Capital S.L.U. Calle Balbina Valverde 15, 282 Madrid, Spain Navarra Iniciativas Empresariales S.A. Paulino Cabellero, 44 Izda., 312 Pamplona, Spain Novartis AG Lichtstrasse 35, 456 Basel, Switserland Novartis Bioventures Ltd. Front Street 131, Hamilton, HM, 12 Bermuda Eduardo Bravo Fernández de Araoz Calle Marconi 1, Parque Technológico de Madrid, 2876 Tres Cantos (Madrid), Spain Claudia D'Augusta Calle Marconi 1, Parque Technológico de Madrid, 2876 Tres Cantos (Madrid), Spain Dirk Büscher Empresarial Can Sant Joan, Avenida de la Generalitat , 8174 Sant Cugat de V Capital Riesgo de la Communidad de Madrid S.A. S.C Paseo de la Castellana 189, 7a Planta 2846 Madrid, Spain Antonio Vilá Casas Calle Ausias Marc, 21 2a, 81 Barcelona, Spain JV Risk Technologies S.L. Calle Ausias Marc, 21 2a, 81 Barcelona, Spain Bankinter S.A. Paseo de la Castellana 29, Palacete, 2a Planta, 2846 Madrid, Spain Bankinter Capital Riesgo I FCR Paseo de la Castellana 29, 2846 Madrid, Spain Commercial Cueto 92 S.L. Don Ramón de la Cruz 9, 286 Madrid, Spain SURO Capital S.A. S.C.R. C/ Marqués de Villamejor, nº 6 1º Izqda, 286 Madrid, Spain INVERSORA BICO S.L. Calle Menéndez Pelayo, 21 oficina 7, 471 Valladolid, Spain Mr. José Ignacio GUZMÁN URIBE Calle Hidra 8, 2823 Madrid, Spain Mr. Adolfo CARVAJAL ISLA Serrano, 1141 Izda., 286 Madrid, Spain Mr. Florent GROS Rue de l'etang 73, 6817 Rixheim, France

2 CX EBIP AGREEMENT S.L.U. Plaza de la Encina, nº 111, núcleo 1, planta 3ª, CP 2876 Tres Cantos (Madrid, Spain Mrs. Ana Maria VIDORRETA GONZALÉZ Paseo Gran Vía 36 4 Dcha, 55 Zaragoza, Spain Mr. Ignacio ALVAREZRENDUELES VILLAR Calle Peguerinos 1B, 2835 Madrid, Spain Mr. Gonzalo BRAVO ZABALGOITIA Calle Nuñez de Balboa, 573 derecha, 281 Madrid, Spain Ramón Carné Plaza Marques de Salamanca 1, 4ºDcha., 286 Madrid, Spain EFG International AG Bahnhofstrasse 12, 81 Zurich, Switzerland A&G Global SicavMidleton Fund Boulevard Emmanuel Servais 2, 2535 Luxembourg Roche Holding AG Grenzacherstrasse 124, 458 Basel, Switzerland Roche Finanz AG Grenzacherstrasse 122, 458 Basel, Switzerland 6) Persons that dispose of,... voting rights (Only to be filled in if art. 7 of the Law applies) Name (& legal form for legal persons) Address (for legal persons) A Please continue entering the information in part II concerning the persons referred to in points 5 and 6 Click 7) Date on which the threshold is crossed 26/4/212 (DD/MM/YYYY) 8) Threshold that is crossed (in %) 3 If the holding has fallen below the lowest threshold, you have the option of not filling in point 1 9) Denominator Please enter the denominator before filling in the data

3 1) Notified details A) Voting rights Previous notification After the transaction s of voting rights Linked to Not linked to the Linked to Not linked to the José Antonio Matji Tuduri 1 Nerel SL subtotal S Novartis AG 1 Novartis Bioventures Ltd subtotal S Antonio Vilá Casas 1 JV Risk Technologies SL subtotal S EFG International AG 1 A&G Global SicavMidleton Fund subtotal S Bankinter SA 1 Bankinter Capital Riesgo I FCR subtotal S Genetrix SL 1 Genetrix Life Sciences AB CX EBIP AGREEMENT SLU subtotal S Commercial Cueto 92 SL 1 Suro Capital SA SCR subtotal S Roche Holding AG 1 Roche Finanz AG subtotal S María José Lafita Torres 1 María Ángeles Lafita Torres 1 Elena Lafita Torres 1 Lucía Lafita Torres 1 Alfredo Lafita Torres 1 Alfredo Lafita Pardo 1 Emilia Torres Rojas 1 Surfolk SL subtotal S Ventech SA Ysios Capital Partners SGECR LSP III Management BV Pilar Matji Tuduri Miguelina Matji Tuduri Manuel Matji Tuduri Jorge Alemany Herrera Biopartners Capital SLU Navarra Iniciativas Empresariales SA Eduardo Bravo Claudia D'Augusta Dirk Büscher Capital Riesgo de la Communidad de Ma Inversora Bico SL José Ignacio Guzmán Uribe Ana Maria Vidorreta Gonzalés Ramón Carné Ignacio AlvarezRendueles Villar Adolfo Carvajal Isla Gonzalo Bravo Zabalgoitia Florent Gros TOTAL % of voting rights Start with "groups" of holders. Calculate subtotals and then finish with the persons who are "alone". The totals, subtotals and % will be updated once you have clicked on <CALCULATE> S B) Equivalent financial instruments After the transaction s of equivalent financial instruments Type of financial instrument Expiration date Exercise period or date that may be acquired if the instrument is exercised % of voting rights TOTAL (in relation to all expiration dates) The totals will be updated once you have clicked on <CALCULATE>

4 TOTAL (Voting rights & Equivalent financial instruments) % of voting rights CALCULATE 11) Chain of controlled undertakings through which the holding is effectively held, if applicable Please describe, or join a diagram in attachment Genetrix S.L. controls Genetrix Life Sciences A.B. and Genetrix Life Sciences A.B. controls CX EBIP Agreement S.L.U.; Bankinter S.A. controls Bankinter Riesgo Capital I, FC.R.; Antonio Vila Casas controls JV Risk Technologies S.L.; José Antonio Matji Tuduri controls Nerel S.L.; A&G Global Sicav Middleton Fund controlled by A&G Global GP S.a.r.l. (Luxembourg) controlled by Asesores y Gestores Financieros S.A. (Spain), controlled by EFG Investment S.A. (Luxembourg) controlled by EFG International AG (Switzerland) ; Novartis AG controls Novartis Bioventures Ltd.; Commercial Cueto 92 S.L. controls Suro Capital S.A. S.C.R.; Roche Holding AG controls Roche Finanz AG; Surfolk SL is controlled by Maria José Lafita Torres, Ángeles Lafita Torres, Alfredo Lafita Torres, Elena Lafita Torres, Lucia Lafita Torres, Alfredo Lafita Pardo and Emilia Torres Rojas. The following legal persons are not controlled by another legal or natural person: Genetrix S.L., Ventech S.A., LSP III Management B.V.; Ysios Capital Partners S.G.E.C.R.; Biopartners Captial S.L.U., Navarra Iniciativas Empresariales S.A., Novartis AG, Bankinter S.A., Capital Riesgo de la Communidad de Madrid S.A. S.C., Commercial Cueto 92 S.L., Inversora BICO S.L. EFG International AG and Roche Holding AG. 12) In case of proxy voting for only one GM will cease to hold / will hold again (DD/MM/YYYY) voting rights as of

5 13) Additional information A) Convertible bonds and rights to subscribe to voting not yet issued Type of financial instrument Expiration date (DD/MM/YYYY) Exercise/Conversion period or date Number that may be acquired if the instrument is exercised/converted B) Shares without voting rights Number C) Remarks The notifying shareholders entered into a lockup agreement dated 3 May 211. The lockup commitments expired on 26 April 212. LSP III Management B.V. is the management company of LSP III Omni Investment Coöperatief U.A. (a collective investment undertaking within the meaning of Article 9, 2 of the Royal Decree of 14 February 28) and exercises the voting rights attached to the shares owned by this fund at its own discretion; Ventech S.A. is the management company of FCPR Ventech Capital III (a collective investment undertaking within the meaning of Article 9, 2 of the Royal Decree of 14 February 28) and exercises the voting rights attached to the shares owned by this fund at its own discretion; Ysios Capital Partners S.G.E.C.R. is the management company of Ysios Biofund I FCR (a collective investment undertaking within the meaning of Article 9, 2 of the Royal Decree of 14 February 28) and exercises the voting rights attached to the shares owned by this fund at its own discretion. Done at Leuven On 14/6/212 (DD/MM/YYYY) Name & capacity An Moonen, Attorneyinfact Signature